imidazole

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imidazole

 [im″id-az´ōl]
1. an organic compound in which two of the five atoms that make up the ring are nitrogen atoms. It is an antimetabolite and inhibitor of histamine and is used as an insecticide.
2. any of a class of antifungal agents that contain this compound.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

im·id·a·zole

(im-id'ă-zōl),
A five-membered heterocyclic compound occurring in l-histidine and other biologically important compounds.
Farlex Partner Medical Dictionary © Farlex 2012

imidazole

(ĭm′ĭ-dăz′ōl′)
n.
1. An organic crystalline base, C3H4N2, that is an inhibitor of histamine.
2. Any of various derivatives of this compound, which often have antifungal, anthelmintic, or antibiotic properties.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

im·id·a·zole

(i-mid'i-zōl)
A five-membered heterocyclic compound occurring in l-histidine and other biologically important compounds.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
We decided to synthesize a series of new optically active Pis bearing benzimidazole pendant groups from an equimolar mixture of dianhydride monomer compound (11) and different diamine derived from amino acids, including isoleucine (lie), valine (Val), methionine (Met), phenylalanine (Phe) (Sch.
(14.) Hennessy D, Steel J.The influence of ruminal absorption on pharmacokinetic behavior of benzimidazole anthelmintics.
[23], quantitative chromatographic determination of several benzimidazole anthelmintic molecules in parasite material by Mottier L et al.
Glennon, "Development and optimisation of a method for the extraction of benzimidazoles from animal liver using supercritical carbon dioxide," Analytica Chimica Acta, vol.
Abstract.- Benzimidazole is a synthetic anthelmintic against which nematode resistance especially in Haemonchus contortus, is emerging at a alarming speed.
It is reported that the combination of the fungicide Carbendazim and the related benzimidazoles, have an effect on testicular and seminiferous tubular atrophy [13,14].
Se recomienda dar tratamiento con pamoato de pirantel a dosis de 10 mg/ kg/dia durante 3 dias, con tasas de curacion del 80% y de erradicacion de huevos del 95%, o tambien se pueden usar benzimidazoles (albendazol: 400 mg/dia durante 3 dias o mebendazol: 100 mg/dia durante 3 dias), con tasas de curacion para el albendazol del 55% y erradicacion de huevos del 98%, y para el mebendazol del 22% y del 82%, respectivamente.
Benzimidazoles can be easily constructed via classical synthetic route from the condensations of 1,2-phenylenediamine with carboxylic acid functional group.