benserazide(redirected from Benzerazide)
an inhibitor of the decarboxylation of peripheral levodopa to dopamine, having actions similar to those of carbidopa. When given with levodopa, benserazide produces higher brain concentrations of dopamine with lower doses of levodopa, thus lessening the side effects seen with higher doses. It is used orally, in conjunction with levodopa, as an antiparkinsonian agent.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
An l-aromatic amino acid decarboxylase (dopa decarboxylase) inhibitor resembling carbidopa in action; given in combination with levodopa as an antiparkinsonian regimen. The benserazide prevents peripheral destruction of levodopa and thus reduces cardiovascular side effects of treatment.
Farlex Partner Medical Dictionary © Farlex 2012
benserazideA dopamine precursor drug given in conjunction with LEVODOPA in the treatment of PARKINSON'S DISEASE to prevent the breakdown of levodopa in the body. A brand name is Madopar.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005