tolbutamide

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tolbutamide

 [tol-bu´tah-mīd]
a sulfonylurea used as a hypoglycemic in patients with type 2 diabetes mellitus whose blood glucose cannot be controlled by diet and exercise alone. The monosodium salt is used to test for insulinoma and diabetes mellitus.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

tolbutamide

(tŏl-byo͞o′tə-mīd′)
n.
A sulfonylurea drug, C12H18N2O3S, used to treat type 2 diabetes.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

tolbutamide

A drug used in the treatment of maturity-onset, non-insulin-dependent DIABETES. A brand name is Rastinon.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
The reaction product, benzenesulfonamide (PhS[O.sub.2]N[H.sub.2]), does not influence the rate showing that it is not involved in a preequilibrium.
Table-1: Aralkyl halides (4a-e) utilized in the synthesis of N-Aralkylated-N-(2,4-dimethylphenyl) benzenesulfonamides (5a-e).
Table-3: Anti-bacterial activity (% age inhibition) of N-Aralkylated-N-(2,4-dimethylphenyl) benzenesulfonamides (5a-e).
N-(5-Chloro-2-methoxyphenyl) -N-ethyl-3,4-dichloro benzenesulfonamide (6d)
N-(5-Chloro-2-methoxyphenyl) -N-benzyl-4-bromo benzenesulfonamide (7a)
N-(5-Chloro-2-methoxyphenyl) -N-benzyl-4-chloro benzenesulfonamide (7b)
N-(5-Chloro-2-methoxyphenyl) -N-benzyl-2,3- dichloro benzenesulfonamide (7c)
Houston et al., "Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides," Bioorganic & Medicinal Chemistry Letters, vol.
Matulis, "Benzenesulfonamides with benzimidazole moieties as inhibitors of carbonic anhydrases I, II, VII, XII and XIII," Journal of Enzyme Inhibition and Medicinal Chemistry, vol.
Tiwari, "Design and synthesis of novel 4-(4oxo-2-arylthiazolidin-3-yl) benzenesulfonamides as selective inhibitors of carbonic anhydrase IX over I and II with potential anticancer activity," European Journal of Medicinal Chemistry, vol.