tolbutamide

(redirected from Benzenesulfonamide)
Also found in: Dictionary, Thesaurus, Encyclopedia.

tolbutamide

 [tol-bu´tah-mīd]
a sulfonylurea used as a hypoglycemic in patients with type 2 diabetes mellitus whose blood glucose cannot be controlled by diet and exercise alone. The monosodium salt is used to test for insulinoma and diabetes mellitus.

tolbutamide

(tŏl-byo͞o′tə-mīd′)
n.
A sulfonylurea drug, C12H18N2O3S, used to treat type 2 diabetes.

tolbutamide

A drug used in the treatment of maturity-onset, non-insulin-dependent DIABETES. A brand name is Rastinon.
References in periodicals archive ?
The reaction product, benzenesulfonamide (PhS[O.sub.2]N[H.sub.2]), does not influence the rate showing that it is not involved in a preequilibrium.
Table-1: Aralkyl halides (4a-e) utilized in the synthesis of N-Aralkylated-N-(2,4-dimethylphenyl) benzenesulfonamides (5a-e).
Table-3: Anti-bacterial activity (% age inhibition) of N-Aralkylated-N-(2,4-dimethylphenyl) benzenesulfonamides (5a-e).
N-(5-Chloro-2-methoxyphenyl) -N-ethyl-3,4-dichloro benzenesulfonamide (6d)
N-(5-Chloro-2-methoxyphenyl) -N-benzyl-4-bromo benzenesulfonamide (7a)
N-(5-Chloro-2-methoxyphenyl) -N-benzyl-4-chloro benzenesulfonamide (7b)
N-(5-Chloro-2-methoxyphenyl) -N-benzyl-2,3- dichloro benzenesulfonamide (7c)
Houston et al., "Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides," Bioorganic & Medicinal Chemistry Letters, vol.
Matulis, "Benzenesulfonamides with benzimidazole moieties as inhibitors of carbonic anhydrases I, II, VII, XII and XIII," Journal of Enzyme Inhibition and Medicinal Chemistry, vol.
Tiwari, "Design and synthesis of novel 4-(4oxo-2-arylthiazolidin-3-yl) benzenesulfonamides as selective inhibitors of carbonic anhydrase IX over I and II with potential anticancer activity," European Journal of Medicinal Chemistry, vol.