benzamide


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Related to benzamide: benzanilide

benzamide

A crystal obtained by the action of ammonia on benzoyl chloride. Chemical derivatives of benzamide are used in a wide range of therapeutics including analgesics (e.g., salicylamide), antiemetics (e.g., metoclopramide), antipsychotics (e.g., sultopride) and other agents.

benzamide

(ben-zam′īd″) [ benzoin + amide]
Any of a class of drugs, including domperidone, metoclopramide, and trimethobenzamide, that block dopamine and serotonin receptors and stimulate acetylcholine receptors in smooth muscle. They are principally used to treat nausea and vomiting.
References in periodicals archive ?
As the reason of fungicide resistance [22], in order to discover new fungicides which possess high efficacy, low toxicity and safety to non-target organisms, a series of heterocyclic/homocyclic benzamide derivatives based on fluopicolide have been designed according to the rule of connecting bioactive substructures together (Fig.
Design, synthesis and antiproliferative activities of novel benzamides derivatives as HDAC inhibitors.
To display the efficiency of the SA as a commercially cost-effective organocatalyst with other catalysts, several results for the synthesis of N-((2-hydroxynaphthalen-1-yl)(4-nitrophenyl)methyl) benzamide (4d) from 4-nitrobenzaldehyde, benzamide (2a), and 2-naphthol (3) are presented in Table 3.
We have deduced from this study that the evaluated product, TRIG (N-N Diethyl Benzamide) could play a significant role in reducing man-vector contact and thereby is likely to reduce the risk of malaria transmission.
2-hydroxy-1-ethyl acetate (22.15%), mono (2-ethylhexyl) ester (2.33%), hexanedioic acid (2.11%), phthalic acid (1.78%), cyclopentane (1.77%), benzamide (1.76%), propanoic acid (1.16%), hydrazine carboxamide (0.93%), pentadecanoic acid (0.91%), hexadecyl acetate (0.81%) and oxalic acid (0.80%) (Fig.
Here we have investigated the low-frequency vibrational motions of salicylamide, benzamide, acrylamide, caprolactam, and sulfanilamide in the solid state by concentrating on the spectral region between 7 and 650 [cm.sup.-1] where crystal lattice vibrations, hydrogen bond bending modes and collective modes, and so forth may occur [26].
Parmar et al., "Appraisal of GABA and PABA as linker: design and synthesis of novel benzamide based histone deacetylase inhibitors," European Journal of Medicinal Chemistry, vol.
Maghsoodlou et al., "Theoretical study, an efficient synthesis route to, and kinetic investigation of, stable phosphorus ylides derived from benzamide," Progress in Reaction Kinetics and Mechanism, vol.
Stomach tissues or cultured cells (HEK293 and RAW264.7) (5 x [10.sup.6] cells/mL) were washed three times in cold PBS with 1 mM sodium orthovanadate and lysed in lysis buffer (20 mM Tris-HCl, pH 7.4, 2 mM EDTA, 2 mM ethylenediaminetetraacetic acid, 50 mM [beta]-glycerophosphate, 1mM sodium orthovanadate, 1 mM dithiothreitol, 1% Triton X-100,10% glycerol, 10 [micro]g/mL aprotinin, 10 [micro]g/mL pepstatin, 1mM benzamide, and 2mM phenylmethanesulfonyl fluoride) for 30 min with rotation at 4[degrees]C.