benzalkonium chloride

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benzalkonium chloride

 [ben″zal-ko´ne-um]
a quaternary ammonium compound used as a surface disinfectant and detergent, topical antiseptic, and antimicrobial preservative.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ben·zal·ko·ni·um chlo·ride

(ben'zal-kō'nē-ŭm klōr'īd),
A mixture of alkylbenzyldimethylammonium chlorides in which the alkyls are long-chain compounds (C8 to C18); a surface-active germicide for many pathogenic nonsporulating bacteria and fungi. Aqueous solutions of this agent have a low surface tension, and possess detergent, keratolytic, and emulsifying properties that aid penetration and wetting of tissue surfaces.
Farlex Partner Medical Dictionary © Farlex 2012

benzalkonium chloride

(bĕn′zăl-kō′nē-əm)
n.
A yellow-white powder prepared in an aqueous solution and used as a detergent, fungicide, bactericide, and spermicide.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

benzalkonium chloride

An antiseptic used in solution for skin and wound cleansing, as a means of sterilizing eye drops and contact lens solutions and as an ingredient in throat lozenges. Allergic reactions occur. Benzalkonium is included in Bradosol lozenges and, for external use only, in Conotrane, Dermol, Drapolene, Emulsiderm and Oilatum Plus.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

antiseptic 

An agent that kills or prevents the growth of bacteria. This term is generally restricted to agents that are sufficiently non-toxic for superficial application to living tissues. These include the preservatives for eye drops and contact lens solutions. Examples of antiseptics are alcohol, benzalkonium chloride, cetrimide, chlorbutanol, chlorhexidine, hydrogen peroxide, thimerosal (or thiomersalate). Other agents that are too toxic to be applied to living tissues are called disinfectants and are used to sterilize instruments and apparatus. See disinfection; ethylenediamine tetraacetic acid; neutralization; sterilization.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann
References in periodicals archive ?
The activity of 4b in these experiments was comparable with that of other ammonium quaternary salts like miramistin and benzalkonium chloride as judged with Pearson's chi-squared homogeneity test.
Caption: Figure 2: Calcein AM staining of MA104 cells after 24 hr incubation: (a) control with MEM, (b) GC Fuji PLUS, (c) GC Fuji PLUS and hexadecyltrimethylammonium bromide 1 wt%, (d) GC Fuji PLUS and hexadecyltrimethylammonium bromide 2 wt%, (e) GC Fuji PLUS and benzalkonium chloride 1 wt%, (f) GC Fuji PLUS and benzalkonium chloride 2 wt%, (g) GC Fuji PLUS and cetylpyridinium chloride 1 wt%, (h) GC Fuji PLUS and cetylpyridinium chloride 2 wt%, (i) GC Fuji PLUS and silver nanoparticles 1 wt%, and (j) GC Fuji PLUS and silver nanoparticles 2 wt%.
Pharmacological modification of the epithelial permeability by benzalkonium chloride in UVA/Riboflavin corneal collagen cross-linking.
van Best, "Topical timolol with and without benzalkonium chloride: epithelial permeability and autofluorescence of the cornea in glaucoma," Graefe's Archive for Clinical and Experimental Ophthalmology, vol.
For Adper Scotchbond 1XT and OptiBond FL with BAC, 60 mg benzalkonium chloride BioXtra (Sigma-Aldrich, St.
The 16 individual disinfectants tested were chloramine-T (0.4% w/v), sodium hypochlorite (0.5% w/v), povidone-iodine and iodophor (1% and 0.1% available iodine, respectively), [H.sub.2][O.sub.2] (3% v/v), KMn[O.sub.4] (1% w/v), benzalkonium and cetylpiridinium chlorides (0.02% and 0.1% w/v, respectively), ethanol and isopropanol (70% v/v), Chlorhexidine digluconate (2% v/v), formaldehyde (3.7% v/v), phenol (5% w/v), phosphoric acid (0.45% v/v), zinc sulphate (0.25% w/v) and thimerosal (0.1 w/v).
(3,5,6) Excellent mydriasis was achieved in pigeons (Columba livid) by using topical d-tubocurarine in 0.025% benzalkonium chloride solution or oil suspension without side effects; however, topical d-tubocurarine in 0.025% benzalkonium chloride solution or in saponin showed minimal to absent mydriasis in cockatoos (Cacatua species) and pigeons.
Background: Long-term use of benzalkonium chloride (BAC)-preserved drugs is often associated with ocular surface toxicity.
The key active ingredient of the handwash is 0.1% benzalkonium chloride which is said to 'kill up to 99.9999%,' of the most commonly occurring bacteria and norovirus within 15-30 seconds, according to the manufacturer, EcoHydra Technologies.
Critical micelle concentrations (cmc) of ADMDHAC at 25 C was found to be 2.851A-10-4 mol.L-1, and its surface tension value at cmc (cmc) was determined to be 30.6 mN.m-1, these data suggested that ADMDHAC could be used as a good alternative of benzalkonium chloride (BC).
(19) Contaminants like benzalkonium heparin, a chemical used to coat catheters in IV-access catheter devices to decrease thrombus formation and infections, interfere with electrodes in older generation of instruments that measured potassium indirectly.
In this study we identified a new synthetic adulterant, benzalkonium chloride, in commercial GSE samples.