light chain disease(redirected from Bence-Jones myeloma)
light chain disease
light chain diseaseA nephropathy which presents with nephrotic range proteinuria and rapidly progressive renal failure due to deposition of electron-dense material within tubular and glomerular basement membranes.
Nephrotic syndrome, heart failure, arrhythmias, liver disease, anorexia, nausea, weight loss, anaemia, increased creatinine, and neurologic disease; similar clinical findings occur in heavy chain deposition.
a collection of objects linked together in linear fashion, or end to end, as the assemblage of atoms or radicals in a chemical compound, or an assemblage of individual bacterial cells.
chain binomial model
model of an outbreak of an infectious disease in which the outbreak is depicted as a series of steps with a binomial statement of the probability of an outcome at each step.
an open chain of atoms, usually carbon, with one or more side chains attached to it.
any of the large polypeptide chains of five classes that, paired with the light chains, make up the antibody molecule. Heavy chains bear the antigenic determinants that differentiate the immunoglobulin classes. See also heavy-chain disease.
a polypeptide occurring in polymeric IgM and IgA molecules.
either of the two small polypeptide chains (molecular weight 22,000) that, when linked to heavy chains by disulfide bonds, make up the antibody molecule; they are of two types, kappa and lambda, which are unrelated to immunoglobulin class differences.
light chain disease
the overproduction of immunoglobulin light chain molecules by certain B cell tumors (plasmacytomas). See monoclonal gammopathy.
used in obstetrics in cattle and horses to snare extremities and for traction. Made of rustproof metal with links designed not to kink or to jam. They have a loop link at each end to facilitate single-handed formation of a loop. The links are shaped so that the ring-grip handles used for traction will grip at any point and stay put with the strongest pull.
a leather lead with a short section of chain at the proximal end. It can be placed over the horse's nose, through the mouth or across the upper gum for greater control.
a chain of atoms attached to a larger chain or to a ring.
strong chain, 1-2 ft (0.5 m) long, at the end of a solid lead. For leading a stallion with little chance of his biting through the lead.
chain termination method