light chain disease(redirected from Bence-Jones myeloma)
light chain diseaseA nephropathy which presents with nephrotic range proteinuria and rapidly progressive renal failure due to deposition of electron-dense material within tubular and glomerular basement membranes.
Nephrotic syndrome, heart failure, arrhythmias, liver disease, anorexia, nausea, weight loss, anaemia, increased creatinine, and neurologic disease; similar clinical findings occur in heavy chain deposition.
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