chimera

(redirected from Bellerophon)
Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

chimera

 [ki-me´rah]
an organism whose body contains different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially.

chi·me·ra

(kī-mēr'ă, ki-),
1. In experimental embryology, the individual produced by grafting an embryonic part of one animal onto the embryo of another, either of the same or of another species.
2. An organism that has received a transplant of genetically and immunologically different tissue, such as bone marrow.
3. Dizygotic twins that exchange immunologically distinct types of erythrocytes.
4. A protein fusion in which two different proteins are linked through peptide bonds; usually genetically engineered. Chimeric antibodies may have the Fab fragment from one species fused with the Fc fragment from another.
5. Any macromolecule fusion formed by two or more macromolecules from different species or from different genes.
[L. Chimaera, G. Chimaira, mythic monster (lit. a she-goat)]

chimera

/chi·me·ra/ (ki-mir´ah)
1. an organism with different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially.
2. a substance created from proteins or genes of two species, as by genetic engineering.chimer´ic

chimera

also

chimaera

(kī-mîr′ə, kĭ-)
n.
1.
a. An organism, organ, or part consisting of two or more tissues of different genetic composition, produced as a result of organ transplant, grafting, or genetic engineering.
b. A gene or protein consisting of parts from two different genes or proteins that are normally distinct, sometimes derived from two different species.
2. An individual who has received a transplant of genetically and immunologically different tissue.

chimera

[kimir′ə, kīmir′ə]
Etymology: Gk, khimaros, fire-breathing monster
an organism carrying cell populations derived from two or more different zygotes of the same or different species. Chimeras include recipients of tissue grafts from other individuals. Compare mosaic.

chimera

Any individual organism or molecule derived from 2 or more species.
 
Embryology
An organism that results when an embryonic part of one organism is grafted onto another.

Genetics
An organism with 2 or more cell lines, genotypes or karyotypes descended from at least 2 zygotes. Chimeras are very rare, only occur in twins and result from chorionic vascular anastomoses, transplantations or double fertilisations and subsequent participation of both fertilised meiotic products in one developing embryo; all hermaphrodites should be karyotyped to evaluate possible chimerism.

Molecular biology
(1) An animal formed from two different embryonic sources. In mouse genetics, targeted mutations produced in embryonic stem cells are recovered by breeding chimeric mice, resulting from the mixture of embryonic stem cells with a genetically distinct blastocyst.
(2) A clone containing genomic DNA from nonadjacent genomic segments or cDNA from two different mRNAs.

Transplantation
The term chimera was once used for a person who had received transplanted tissue—e.g., bone marrow surviving in a recipient.

chi·me·ra

(kī-mēr'ă)
1. The individual produced by grafting an embryonic part of one animal onto the embryo of another, either of the same or of another species.
2. An organism that has received a transplant of genetically and immunologically different tissue, such as bone marrow.
3. Dizygotic twins that have immunologically distinct types of erythrocytes.
4. A protein fusion in which two different proteins, usually from different species, are linked through peptide bonds; usually genetically engineered. Chimeric antibodies may have the Fab fragment from one species fused with the Fc fragment from another.
5. Any macromolecule fusion formed by two or more macromolecules from different species or from different genes.
[L. Chimaera, G. Chimaira, mythic monster (lit. a she-goat)]

chimera

An organism that contains a mixture of genetically different cells derived from more than one ZYGOTE. A chimera may, for instance, occur as a result of fertilization by more than one spermatozoon; fusion of two zygotes; an ALLOGENEIC bone marrow graft; cell exchange between dizygotic twin fetuses; or combination of portions of embryos of different species. Compare MOSAICISM. The term derives from the name of a mythical monster with a lion's head, a goat's body, and a serpent's tail.

chimera, chimaera

1. a mythological, fire-spouting monster with a lion's head, goat's body and serpent's tail.
2. an animal whose body contains different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially; i.e. an individual composed of a mixture of genetically different cells.

chimera protein
see fusion protein.
References in periodicals archive ?
Both Melikertes/Palaimon and Bellerophon and Pegasus at the Peirene Fountain constituted part of Corinth's mythical history, which functioned to help shape the Corinthians' civic identity Commemoration of these mythical stories through religious ceremonies and festivals was a part of history-keeping in Corinth.
Bellerophon Therapeutics is a clinical-stage biotherapeutics company that develops therapies at the intersection of drugs and devices that address unmet medical needs in the treatment of cardiopulmonary and cardiac diseases.
At the beginning of the play, Perseus arrives to help Bellerophon in his quest against the Chimaera.
an ass with wings glued on his back, walking beside a decrepit old man, so that you would call the one Bellerophon and the other Pegasus, but laugh (78) at both.
While the waters of that "poor mother's heart" (7:145) refresh Bellerophon, as he awaits the Pegasus's arrival, it is not until a little boy's "quiet tear-drops" fall and mingle with its waters that the horse finally appears to him (7:153).
DEATH PLUNGE J Gary Currie FATAL FLAW The crane that suffered catastrophic failure on Wednesday and sent construction worker Gary plummeting to his death also buckled and broke in same joint one year ago TRAGIC J Gary Currie fell to his death 'SORRY' J The crane's owner Donald Craig, right, at Buchanan House PROOFJ Close-up shows the machine is broken in the same place WRECKED 3 The cherrypicker after the fatal accident in Glasgow LOCATION J Cherrypicker on site at Bellerophon Drive in Penicuik BUCKLED J The first time the crane broke
Supposedly, Proitos sent something of this sort along with Bellerophon.
Since Pegasus did not exist in reality, but only in thought, being the winged horse captured by Bellerophon is an essential property of Pegasus.
DING DING AND A PRAYER The good vicar gets on his bike HIPPY DAYS Dazzle, Mary, Denny CANNON FEEDER On Bellerophon WELL-SUITED Waiting for the verdict
In 1875 Bradley brought out The New Minnesinger as Arran Leigh, and in 1881 the two women together, as collaborators for the first time, had published Bellerophon as Arran and Isla Leigh.
Vector sequences were removed from resulting sequences using VecScreen, forward and reverse sequences were assembled using ContigExpress (Invitrogen), and the presence of chimeric sequences was tested using Bellerophon (Huber et al.