Behçet's disease

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Behçet's disease

[bā′sets]
Etymology: Hulusi Behçet, Turkish dermatologist, 1889-1948
a rare syndrome that includes a severe, chronic, multisystem inflammatory illness of unknown cause; it mostly affects young males and is characterized by severe uveitis and retinal vasculitis. Other signs include optic atrophy and small, shallow, painful white or grey lesions of the mouth and the genitals, indicating diffuse vasculitis. It may involve all organs and affect the central nervous system. Immunosuppressive therapy may be considered. The disease is common in Japan, Turkey, and Israel, but rare in the United States. Also called Behçet's syndrome.

Behçet's disease

Behçet syndrome An idiopathic multisystem condition most common in the Middle East; ♂:♀ ratio 2:1, aged 15–40 Clinical Pustules, aphthous stomatitis–90%, genital ulcers; vasculitis; erythema nodosa–80%, meningoencephalitis, synovitis, uveitis Lab ↑ ESR, ↑ Igs, anemia Management Symptomatic, corticosteroids
References in periodicals archive ?
Elevated oxidative stress markers and its relationship with endothelial dysfunction in BehCet disease.
Additionally, the report provides an overview of key players involved in therapeutic development for Behcet Disease and features dormant and discontinued projects.
Trabeculectomy with mitomycin-C in uveitic glaucoma associated with Behcet disease.
Iran is also among the geographical regions with incidence of Behcet Disease.
Behcet disease is a multisystem vascular inflammatory disease of unknown origin.
Although infection remains an important differential in our diagnosis of patients complaining of oral and genital ulceration with ocular involvement, with studies showing an increase in the streptococcal flora in this cohort of patients, current evidence has shown that the underlying pathogenesis of Behcet disease is complex and it is likely that an environmental stimulus triggers an abnormal immune response in a genetically susceptible host [3].
Objective: The aim of this study was to evaluate the erectile dysfunction (ED) in patients who have been followed up and treated with the diagnosis of Behcet disease.
Samples were taken from 84 Japanese MS patients 14-68 years of age (mean age, 40 years), 55 patients 18-64 years of age (mean age, 45 years) with other neurological diseases (12 with chronic cerebrovascular disease, 14 with amyotrophic lateral sclerosis, 12 with Parkinson disease, 5 with polyneuropathy, 4 with Behcet disease, 5 with meningitis, and 3 with Guillam-Barre syndrome), and 45 patients 19-67 years of age (mean age, 43 years) with nonneurological diseases.
Ulcerations in a neonate can be due to a number of causes other than NLE, including Behcet disease, hemangiomas, herpes virus infection, leishmaniasis, and Langerhans cell histiocytosis.
Neurological findings of Behcet disease have been classified in great detail.