BAX


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BAX

BAX
A gene located on chromosome 19q13.3-q13.4, which encodes Bax, which belongs to the BCL2 family of proteins with which it forms a heterodimer, together acting as anti- or pro-apoptosis regulators, depending on whether Bax or Bcl-2 is greater. BAX expression is regulated by p53, the tumour suppressor, and is involved in p53-mediated apoptosis.

Bax
A 21-kD protein encoded by BAX, located on chromosome 19q13.3-q13.4, which has significant homology with Bcl-2, the apoptosis repressor, with which it forms a heterodimer. Overexpression of Bax compared to Bcl-2 signifies apoptosis.
References in periodicals archive ?
Quantitative Real-time PCR Amplification of Bax, Bcl-2 and [beta]-Actin Gene in Dog: The concentration of PCR amplification products of Bax, Bcl-2 and [beta]-actin genes were detected by the ultraviolet spectrophotometer made by General Analysis of General Instrument Co., Ltd.
An English Heritage blue plaque, unveiled in 1993, commemorates Bax at his birthplace, 13 Pendennis Road in London.
Above: Myles Bax (third from left) with members of the Robotical team
As club secretary, Bax is fairly happy with where the club is at present.
Participants who complete the training module will be assessed and will be given a national certification once they pass, Bax said.
Histological staining indicated accumulation of NF-[kappa]B, Akt, Bcl-2, and Bax in the model group retina, which was not observed in the control retina, but the levels of these proteins appeared to differ between time points in each group (p <0.05).
The Bcl-2 family involves antiapoptotic members like Bcl-2 and Bcl-Xs and proapoptotic members like Bax, Bad, Bak, and Bcl-Xs.
"And today Mike Bax allows bloodthirsty hunters on to his land to gun down pheasants, many of which die in agony." A Wildlife Trust spokesman said: "Mike Bax purchased Street End Wood, next to his farm, in 2007 at which time the local shoot was already in place.
Shortly after the formation of the business, DuPont pioneered Nobel-prize-winning PCR technology in commercial food safety testing with the BAX System for pathogen detection.
The procaspase-3 protein contents, and Bcl-2 mRNA and protein contents were significantly decreased while caspase-3 protein contents, and Bax mRNA and protein contents were concomitantly increased in the concentration-dependent manner in FA groups (P 0.
Immunohistochemical investigations for the expression of the proapoptotic protein (Bax) and the expression of macrosialin cluster of differentiation (CD68).