basolateral

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ba·so·lat·er·al

(bā'sō-lat'er-ăl),
Basal and lateral; specifically used to refer to one of the two major cytologic divisions of the amygdaloid complex. See: amygdaloid body.
Farlex Partner Medical Dictionary © Farlex 2012

ba·so·lat·er·al

(bā'sō-lat'ĕr-ăl)
Basal andlateral; specifically used to refer to one of the two major cytologic divisions of the amygdaloid complex.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
In the renal cortex, immunolight microscopy revealed strong expression of AQP1 in the apical and basolateral membrane of epithelial cells at the proximal straight / convoluted tubule of ND, respectively (Figs.
Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basolateral membrane of kidney collecting duct cells.
The acinar basolateral membrane has receptors for secretion of cholecystokinin, acetylcholine and vasoactive intestinal peptide.
Anions are taken up at the basolateral membrane primarily by organic anion transporter (OAT) 1 and 3 and secreted at the apical membrane by the multidrug resistance proteins (MRP) 2 and 4 (Masereeuw et al., 1999), while cations are mainly taken up by organic cation transporter (OCT) 2 and are eliminated by multidrug and toxin extrusion proteins (MATE) 1 and 2K (Biermann et al., 2006; Cetinkaya et al., 2003; Sauzay et al., 2016) and P-glycoprotein (P-gp).
The work horses for detoxification are 1) MRP1, the transmembrane transporter serving most cells in the body for exporting toxins to circulation, 2) OATP, the basolateral membrane transporter which moves toxin conjugates from the blood into the hepatocytes or renal tubule epithelial cells, and 3) MRP2, the apical transporter that moves toxin conjugates (and some bile salts) into the bile canaliculus or renal proximal tubule lumen.
The heterodimeric organic solute transporter OST[alpha]-OST[beta] (OST[alpha], gene SLC51A; OST[beta], gene SLC51B) is expressed in the basolateral membrane of enterocytes and effluxes BS to the portal blood.
Based on the rat model studies mainly, the bile salt independent pathway needs chemical and electrical driving forces generated by the Na-K ATPase in the basolateral membrane [6].
NIS was positive in the basolateral membrane in up to 10% of the cells of ectopic samples 3, 4, and 5.
Grade 0: no reaction or <10% reactivity in tumour cells; grade 1+: weak reactivity >10% of the tumour cells; with reactivity only in part of the membrane; grade 2+: moderate reactivity in >10% of the cells, with staining across the lateral and basolateral membrane; grade 3+: strong reactivity with intense staining of the lateral and basolateral membrane in >10% of the cells.
Most of these solutes are carried via a series of [Na.sup.+]-coupled cotransporters or exchangers, which utilise the transmembrane [Na.sup.+] gradient generated by NKA on the basolateral membrane [42].
In order to secrete chloride across the apical membrane of the epithelial cells, the basolateral membrane has to establish a driving force for anion efflux via anion channels (e.g., cystic fibrosis transmembrane conductance regulator, CFTR, or [Ca.sup.2+]-sensitive chloride channels) located in the apical membrane (Figure 2).
The general finding of Aqp3 protein in the basolateral membrane of chloride cells suggests that this aquaporin is participating in cell volume regulation and may take part in nitrogen excretion as well.