Naked Nucleus

(redirected from Bare Nucleus)
Cytology A nucleus in a cytologic preparation that is virtually devoid of cytoplasm, which is typically seen in cell degeneration. In a pap smear, naked nuclei are non-specific findings and cells may correspond to degenerated endocervical cells, autolysed cells of postmenopausal atrophy, dysplasia, carcinoma in situ, nonkeratinizing cervical cancer, endocervical, endometrial, and metastatic cancer. Naked nuclei are also a soft criterion for diagnosing ovarian endometriosis, which may be mixed with slightly elongated, cytoplasm-poor cells with hyperchromatic nuclei—definitive diagnosis of endometriosis requires the presence of endometrial glands, stroma and haemorrhage
Surgical pathology In a pathology specimen, naked nuclei are typical of undifferentiated/small cell carcinomas of any site—e.g., in small cell carcinoma of lung and elsewhere—and usually have friable—‘taffy-pull’—nuclei and scant or absent cytoplasm
References in periodicals archive ?
Once gas and dust in the coma disperse into space, relatively little new material emerges from the comet to replace it, leaving behind a bare nucleus.
These investigations revealed that a highly charged ion -- in many cases, little more than a bare nucleus -- traveling toward a metal surface can extract and capture a large number of electrons from its target in an extraordinarily short time.