Baltimore Longitudinal Study of Aging


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Baltimore Longitudinal Study of Aging (BLSA)

a long-range examination of interrelations between multiple correlates of aging. Although men of varied backgrounds were selected for the original study (1955) in order to explore uncontrolled factors that might lead to new knowledge regarding aging, the BLSA now includes both men and women.

BLAT

Abbreviation for:
Baltimore Longitudinal Study of Aging
BLAST-Like Alignment Tool

Molecular biology
BLAST-Like Alignment Tool. A DNA/protein sequence analysis program to find sequences of ≥ 95% sequence similarity of ≥ 40 bases or more in length. BLAT may miss more divergent or shorter sequence alignments. BLAT on proteins finds sequences of 80% and greater similarity of length 20 amino acids or more.

Clinical trials
Baltimore Longitudinal Study of Aging. A trial which evaluated the effects of nonsustained ventricular tachycardia and arrhythmias on mortality. The BLAT data indicated no new coronary events at 10 years of follow up in 98 older individuals who had no prior clinical evidence of heart disease.
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A separate presentation at the meeting suggested that higher levels of free testosterone may correlate with a higher risk for prostate cancer, but the data for that analysis came from the Baltimore Longitudinal Study of Aging, which reported no correlation between testosterone and prostate cancer risk several years ago, he noted.
The first was selected from 681 men over 55 years old who had PSA assays as part of the Baltimore Longitudinal Study of Aging (BLSA).
The Baltimore Longitudinal Study of Aging tracks memory changes in 500 volunteers every two years.
The study involved 642 participants, ages 31 to 96, all part of the Baltimore Longitudinal Study of Aging, an ongoing multidisciplinary study at the NIA.
National Institute on Aging (NIA)-supported researchers at the Columbia Presbyterian Medical Center (CPMC) in New York City and NIA's Baltimore Longitudinal Study of Aging at The Johns Hopkins University in Maryland are looking at estrogen.

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