bactericidal permeability-increasing protein


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia.

BPI

A gene on chromosome 20q11.23 that encodes a lipopolysaccharide-binding protein associated with human neutrophil granules, which has
bactericidal activity on gram-negative bacteria.

bactericidal permeability-increasing protein

A protein that acts on bacteria, especially meningococci, to increase their membrane permeability and so kill them. It also binds to and clears bacterial toxin. The substance has been proposed as a one of the modalities for treating bacterial MENINGITIS.
Mentioned in ?
Medical browser ?
Full browser ?