CASC3

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CASC3

A gene on chromosome 17q11-q21.3 that encodes a widely expressed protein which is a core component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC marks the position of the exon–exon junction in the mature mRNA and thereby influences downstream processes of gene expression, including mRNA splicing, nuclear mRNA export, subcellular mRNA localisation, translation efficiency and nonsense-mediated mRNA decay. It interacts with EIF4A3, MAGOH, NXF1 and RBM8A, as well as with STAU in an RNA-dependent fashion.
 
Molecular pathology
CASC3 is overexpressed in the breast and in gastric cancers.
References in periodicals archive ?
SKILL SET Bar-Barian BTZ stars (from left) Tank, Zeeny and BeeJay, bridge the gap between young and old in Scottish rap.
He received radiation therapy to the thoracic spine and completed 2 cycles of CyBorD regimen (cyclophosphamide 300mg/[m.sup.2] by mouth, BTZ 1.5mg/[m.sup.2] subcutaneous, and dexamethasone 40 mg by mouth each on days 1, 8,15, and 22).
An extensive PubMed search yielded 35 events of BLI, 5 of which occurred with readministration of BTZ after resolution of initial BLI.
In this section we would like to study the horizon structure of the 2 + 1 dimensional BTZ black hole.
To investigate the CM energy of the collision on the horizon of the BTZ black hole, we have to derive the 2 + 1 dimensional "4-velocity" component of the colliding particle in the background of the 2 + 1 dimensional BTZ black hole.
The macroinvertebrate communities of BTZ wetlands have not been characterized, nor has the effect of increased agriculture on these communities.
The BTZ wetlands we studied (n =14) were located in the Lakeland and Athabasca regions near Lac La Biche, Alberta, Canada (UTM: Zone 12U, 437803E, 6069387N, NAD83/WGS84).
(BTZ) "aukso antrankiai" (darbo sutartyje numatytos privilegijos administratoriui ir nuobaudos, jam pirma laiko nutraukiant sutarti).
(11) It was shown previously that mainly HPTs have very low-vapor pressure and show best photopermanence followed by BTZ, BP, and then Ox.
Address : Gebude- Und Fensterreinigungsdiensten Fr Das Bfw Oberhausen Und Das Btz Rhein-Ruhr Ggmbh
Contract notice: new vocational training and technology center (btz) with underground parking - b38012.2 close masonry ba2
Tender notice number : CE BTZ 30/2018-19 PROVN OF OTM ACCN AT BIKANER