AURKA

(redirected from BTAK)

AURKA

A gene on chromosome 20q13 that encodes Aurora kinase A, which is involved in regulating many early mitotic events such as entry into mitosis. Aurora A levels rise during the G2 phase and peak early in mitosis. It is highly expressed in the testes, as well as in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
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Aurora kinases (also known as BTAK and STK15) are a family of serine-threonine kinases that are believed to play multiple roles in the development and progression of cancer, by acting as regulators of cell proliferation, by transforming normal cells into cancer cells and by down-regulating p53, one of the body's natural tumor suppressors.
Aurora kinases (also known as BTAK and STK15) are a family of serine-threonine kinases that are believed to play multiple roles in the development and progression of cancer by acting as regulators of cell proliferation, by transforming normal cells into cancer cells and by down-regulating p53, one of the body's natural tumor suppressors.