BPTF


Also found in: Acronyms.

BPTF

A gene on chromosome 17q24.3 that encodes a histone-binding component of nucleosome-remodelling factor (NURF), a protein complex which catalyses ATP-dependent nucleosome sliding and facilitates transcription.

Molecular pathology
High levels of FAC1/BPTF may be found in foetal brain and in patients with neurodegenerative diseases (e.g., Alzheimer’s disease).
References in periodicals archive ?
NAFLD&NASH to HCC PBC&PSC to HCC The highly activated ACTA2, AIFM1, APP, ACTB, ADRB2, APP, network biomarkers EGFR, GRB2, NEDD8, CSNK2A1, EGFR, for potential SHC1, TUBA1C, TUBB6, HUWE1, LMNB1, PCK1, inhibition strategy IL4R, GPR37, FRAT2, PPP2CA, SMAD5, of drug design HIST2H2BE, HSPB1, TSC22D1, ESR1, PGR, ZNF480, TIMP1, RYR2, FRAT2, ALDOB, ZYX, YBX1, HIST2H2BE, ZNF480, TP53, STAT5A, AR, H3F3A, TIMP1, ALDOB, TELO2, PXN, TBP, IGF2, AR, TP53, SRF, REPIN1, HSF1, ETS1, NRF1, STAT5A, STUB1, RFC5, RPL30, RPL23A, SP1, SP3, TRMT1, GSK3B, UBC, CEBPA, BPTF, ETS1, ALB, and MIR21 MDC1, RFC5, RPL30, TRMT1, UBC, GSK3B, TF, and MIR21 The repressed ALK and GATA1 CEBPE and GATA1 network biomarkers for potential activation strategy of drug design
WASHINGTON -- The Bulk Pharmaceuticals Task Force (BPTF) has thrown its support behind the Generic Drug and Biosimilar User Fee Act, asserting it would better protect the U.S.
The June 30 meeting focused on funding for GDUFA, where FDA noted, "Congress will have the final role in determining the precise fee structure after the negotiated plan is presented to Congress for inclusion in user fee legislation," but no change was made from the 80/20 proposal reiterated by GPhA, the European Fine Chemicals Group (EFCG) and SOCMA's Bulk Pharmaceutical Task Force (BPTF).