Btk

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Btk

Abbreviation for Bruton tyrosine kinase.
Farlex Partner Medical Dictionary © Farlex 2012

BTK

A gene on chromosome Xq21.33-q22 that encodes a protein which plays a central role in B-cell development, differentiation and signalling. Binding of antigens to the B-cell antigen receptor (BCR) triggers signalling that leads to B-cell activation. 

Molecular pathology
Defects of BTK cause X-linked agammaglobulinaemia (OMIM:300755), as well as X-linked hypogammaglobulinaemia and isolated growth hormone deficiency (OMIM:307200).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

Bruton's agammaglobulinemia tyrosine kinase (Btk)

An enzyme vital for the maturation of B cells.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
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