BMP7


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BMP7

A gene on chromosome 20q13 that encodes bone morphogenetic protein-7, which plays a key role in cartilage formation, osteoblast differentiation, renal development and repair, and induces the production of SMAD1.
References in periodicals archive ?
cuniculus and nine different mammals, ten sequences each of GDF8, inhibin and BMP7 of same animals were also retrieved from GenPept for phylogenetic systematics.
During our gene identification, mutations in BMP7 and Slc38a1 genes had occasionally emerged; BMP7 especially was previously identified critical for cochlear axis specification.
Further HTS experiments are needed to expand coverage for the TDS-related candidate genes, such as SHH, FGF10, BMP7, HOXA4, DGKK, and TGFBR3 (Carmichael et al.
BMP7 triggers production of mesenchymal adipose cells to brown adipose cells.
BAT mass and its metabolic activity could be up-regulated by several transcription factors, activating proteins, and hormones (e.g., molecular determinants PRDM16 and BMP7).
Additionally, miR-483 might participate in regulating the balance between promoters and inhibitors in renal fibrosis by regulating the expression of some cytokines, such as bone morphogenetic protein-7 (BMP7), transforming growth factor beta (TGFp), hepatocyte growth-promoting factor, and connective tissue growth factor (CTGF).
BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo.
BMP-2 and BMP7 play a significant role in skeletal development and are potent inducers of bone formation [18].
Cho et al., "Electrospun fibers immobilized with bone forming peptide-1 derived from BMP7 for guided bone regeneration," Biomaterials, vol.
Endoglin interacts with several ligands of the TGF-[beta] family, including BMP2, BMP7, and activin.
They are "ideal" natural scaffolds for new bone growth, according to company officials, because they are processed to retain osteoinductive properties by preserving endogenous growth factors including BMP2, BMP4 and BMP7 to help support new bone formation.