BMP2B | definition of BMP2B by Medical dictionary
BMP4 (redirected from BMP2B)
BMP4 A gene on chromosome 14q22-q23 that encodes bone morphogenetic protein-4, which plays a key role in formation of teeth, limbs and bone from mesoderm, as well as fracture repair.
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References in periodicals archive
Reddi, "Stimulation of chondrogenesis in limb bud mesoderm cells by recombinant human bone morphogenetic protein 2B (BMP2B
) and modulation by transforming growth factor [beta]1 and [beta]2," Experimental Cell Research, vol.
The ectopic expression of shh or bmp2b
in the blastema induced excess bone deposition and altered the patterning of the regenerate; and the forced expression of the Bmp antagonist Chordin disrupted fin growth and osteoblast differentiation (Smith et al, 2006).
Bone patterning is altered in the regenerating zebrafish caudal fin after ectopic expression of sonic hedgehog and bmp2b
or exposure to cyclopamine.