GDF.ah.7

(redirected from BMP12)

GDF.ah.7

A gene on chromosome 2p24.1 that encodes a member of the bone morphogenetic protein (BMP) family of secreted signalling molecules, which regulate diverse processes in growth, repair and embryonic development, and may provide an inductive signal from the roof plate for specifying the neuronal identity in the dorsal spinal cord.
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References in periodicals archive ?
Kunz et al., "BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells," Cytotherapy, vol.
This causes a protein - BMP12 - to be produced, suppressing feather growth and causing the bird to have an outstanding bald neck.
The ASC-encapsulated scaffolds stimulated with BMP12 meanwhile exhibit increased tenogenic response as established in previous studies [20, 37], with 10-fold rise in tenascin and 2-fold increases in scleraxis and tenomodulin.