ARNTL2

(redirected from BMAL2)

ARNTL2

A gene on chromosome 12p12.2-p11.2 that encodes a basic helix-loop-helix protein which forms a heterodimer with CLOCK and binding an E-box element, activating transcription. This transactivation is inhibited by clock genes PER2 and CRY1.
References in periodicals archive ?
Four period (perla, perlb, per2, and per3), 6 cryptochrome (cry1a, cry1b, cry2a, cry2b, cry3, and cry4), 3 clock (clock1a, clock1b, and clock2), and 3 bmal (bmal1a, bmal1b, and bmal2) genes have been cloned from D.
A rhythm of lower amplitude has been shown for clock genes in zebrafish embryonic cell lines as PAC-2 (clock, [20]) and in Z3 cells (clock, per1, per3, bmal1, and bmal2, [39]), as well as in cultured zebrafish heart and kidney (clock [20]) maintained under constant conditions.