BLOSUM


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BLOSUM

Blocks Substitution Matrix. A substitution matrix in which scores for each position are derived from observations of the frequencies of substitutions in blocks of local alignments in related proteins.

Sequences that are more identical than 62% are represented by a single sequence in the alignment, to avoid over-weighting closely related family members.
References in periodicals archive ?
The Blosum scoring matrix was selected with a gap penalty of 10 and a gap extension penalty of 0.05.
Background frequencies for residue variability estimates: BLOSUM revisited.
Abbreviations used ABC Transporter ATP-binding cassette transporter BLAST Basic Local Alignment Search Tool BLOSUM BLOcks of Amino Acid Substitution Matrix EGF Epidermal growth factor EGFR Epidermal growth factor receptor ErbB2 Member of the ErbB protein family.
BLAST uses a scoring matrix such as PAM or BLOSUM to calculate an alignment score, which measures the significance of sequence similarity between any two sequences.
The BLOSUM matrices, proposed by Steven Henikoff y Jorja G.
In future work, additional experimentation should be performed, including experimentation with sequences of nucleic acids, the use of other algorithms to find initial sequence alignments and the use of other scoring schemes based on PAM or BLOSUM matrices.
KUNSTHALLE BERN * June 6-AugUSt 3 * Curated by Lionel Bovier * Between 1961 and 1965, an artist using the pseudonym Vern Blosum made forty-four paintings of common objects in the style of Pop art.
Between 1961 and 1964, American Pop artist Vern Blosum produced forty-four canvases illustrating flowers, animals, and infrastructural fixtures outside his Manhattan studio.
I discovered Vern Blosum's painting 25 Minutes, 1962, in Cardwell Jimmerson's "Sub-Pop," an impeccably researched exhibition that sought to diminish the aura of historical inevitability surrounding the Pop art canon.