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Related to BK virus: Polyomavirus
a human polyomavirus, in the family Papovaviridae, of worldwide distribution, that produces kidney infections that are usually subclinical in immunocompetent people.
[initials of patient from whom first isolated]
BK virusA small human polyomavirus which, like the JC virus, can transform infected cells in culture; up to 80% of the general population (US) have been exposed to it.
Primary BKV infection is usually subclinical, most common in early childhood, persists in renal epithelium and may become reactivated, causing severe tubulointerstitial nephritis, and cystitis in BM transplant recipients or in immunocompromised patients—e.g., those with hyper-IgM immunodeficiency syndrome; BKV may cause encephalitis.
Serology—IgM, IgG antibodies; PCR; T2-weighted MRI.