BK virus

(redirected from BK polyomavirus)

BK vi·rus

a human polyomavirus, in the family Papovaviridae, of worldwide distribution, that produces kidney infections that are usually subclinical in immunocompetent people.
[initials of patient from whom first isolated]
Farlex Partner Medical Dictionary © Farlex 2012

BK virus

A small human polyomavirus which, like the JC virus, can transform infected cells in culture; up to 80% of the general population (US) have been exposed to it.

Clinical findings
Primary BKV infection is usually subclinical, most common in early childhood, persists in renal epithelium and may become reactivated, causing severe tubulointerstitial nephritis, and cystitis in BM transplant recipients or in immunocompromised patients—e.g., those with hyper-IgM immunodeficiency syndrome; BKV may cause encephalitis.
 
Diagnosis
Serology—IgM, IgG antibodies; PCR; T2-weighted MRI.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

BK virus

Infectious disease A small human polyomavirus which, like the JC virus, can transform infected cells in culture; 1º BKV infection is usually subclinical, is most common in early childhood, persists in renal epithelium and may be reactivated, causing severe tubulointerstitial nephritis, and cystitis in BM transplant recipients, or in the immunocompromised Pts–eg, those with hyper-IgM immunodeficiency syndrome; BKV may cause encephalitis Diagnosis Serology–IgM, IgG antibodies; PCR, T2-weighted MRI. See Polyomavirus. Cf JC virus.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
BK polyomavirus is associated with nephropathy and ureteric stenosis in kidney transplant recipients as well in other types of transplant recipients.
This may be what occurred with the related BK polyomavirus as it was cultured to generate material for the WHO International Standard (4).
Van Ghelue et al., "BK polyomavirus with archetypal and rearranged non-coding control regions is present in cerebrospinal fluids from patients with neurological complications," Journal of General Virology, vol.
Polyomavirus.--The polyomavirus family includes BK Polyomavirus, JC polyomavirus, as well as Simian virus 40 (SV-40), and the recently described Merkel cell polyomavirus, among others.
Infection with BK polyomavirus (BKPyV) or JC polyomavirus causes substantial illness and death in immunocompromised populations, including transplant recipients and HIV patients (1).
Table 1 Commonly Used Abbreviations Related to BK Virus Abbreviation Term BKV BK virus, polyomavirus BK, BK polyomavirus BKVN BKV nephritis, BKV nephropathy BKPyV BK polyomavirus, polyomavirus BK BKVAN BK virus-associated nephropathy PVAN Polyomavirus-associated nephropathy PyV Polyomavirus PyVAN Polyomavirus BK nephropathy, polyomavirus nephropathy, polyomavirus-associated nephropathy BKVAN BK virus associated nephropathy
BK polyomavirus (BKV) is a common pathogen of kidney transplant recipients, which can result in impaired graft function and inferior graft survival [1].
Homma, "Evolution of the BK polyomavirus: epidemiological, anthropological and clinical implications," Reviews in Medical Virology, vol.