HOXD13

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HOXD13

A gene on chromosome 7p15.2 that encodes a sequence-specific DNA-binding transcription factor of a developmental regulatory system, which provides cells with specific positional identities on the anterior-posterior axis.

Molecular pathology
Expansion of a polyalanine tail in the HOXD13 protein is linked to hand-foot-uterus/genital syndrome.
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