BCR/ABL gene

BCR/ABL gene

(jēn)

A fusion gene produced when a segment of the Abelson protooncogene, ABL, from chromosome 9, translocates to the major breakpoint cluster region (M-BCR) on chromosome 22. The fusion gene produces a specific protein, P210. This fusion gene is found in chronic myelocytic leukemia (CML).

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