The company added BCOP
certified pharmacists are increasingly recognised for their specialised training, knowledge and skills in oncology practice.
classifies tested compounds on a scale of none, mild, moderate or severe irritants.
Another man who did a lot of work was Douglas Turner, who also founded a Trust in his name administered by BCOP
For example, the isolated eye tests IRE and CEET as well as the BCOP
and HET-CAM tests are accepted by some European regulatory authorities on a case-by-case basis for the identification of severe eye irritants for the purposes of classification and labeling within the European Union on chemicals and products.
chief executive Marcus Fellows said it would not have achieved its success without the help and support of numerous individuals and organisations, "including its own employees, volunteers, supporters, close working suppliers, contractors and professionals who have helped us over the last 70 years."
TABLE 1: ENDPOINTS AND OECD-VALIDATED ALTERNATIVE IN VITRO TEST METHODS ITS: Integrated testing strategy Toxicological Endpoint Test Method Test method description Ocular irritation BCOP
Opacity and permeability to fluorescein measurement ICE Swelling of the cornea, opacity, fluorescein retention, morphology Fluorescein leakage Measurement of test fluorescein leakage trough a mono-layer of confluent cells MDCK CB997 Het-Cam Observation of the Irritating effects (hyperaemia, haemorrhages, coagulation) EpiOccular, HCE Human corneal epithelium SkinEthic model.
grounds staff had the task of creating the pounds 125,000 garden, which is open to all 50 residents of the home but has been specially designed with the 12 people in the dementia wing in mind.
A decision was taken to make the pounds 1,000 donation to Birming ham-based, BCOP
, Broadening Choices for Older People, who will spend the money creating the room at one of its nursing homes.
Four of them, the Isolated Chicken Eye test (ICE), the Bovine Corneal Opacity and Permeability assay (BCOP
), the Short Time Exposure test (STE) and the Reconstructed human Cornea-like Epithelium test (RhCE) can be used to identify chemicals that do not require GHS classification (No Cat.) or that induce serious eye irritation (GHS Cat.
The charity BCOP
(Broadening Choices for Older People) won Chez Jules's Credit Crunch Lunch competition.
The Phototoxicity video is the second training video produced by ITVS with EPAA's support--the first described the Bovine Corneal Opacity and Permeability (BCOP
) assay (OECD TG 437).
The nonanimal methods used were: the bovine corneal opacity and permeability (BCOP
) assay (Gautheron et al., 1994), the Cytosensor[TM] microphysiometer (CM) assay (Hartung et al., 2010), and the EpiOcular[TM] (EO) time to toxicity assay (MatTek Corporation, Ashland, MA) (Stern et al., 1998).