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a cytotoxic alkylating agent of the nitrosourea group, used as an antineoplastic agent, primarily against brain tumors, multiple myeloma, colorectal carcinoma, Hodgkin's disease, and non-Hodgkin's lymphomas. Called also BCNU.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
An antineoplastic agent.
Farlex Partner Medical Dictionary © Farlex 2012
BCNUA chemotherapeutic related to lomustine (CCNU) and semustine, which partially overlaps the activity/toxicity of alkylating agents.
Hodgkin lymphoma, non-Hodgkin lymphoma, melanoma, myeloma, brain tumours, gastrointestinal carcinomas; BCNU crosses the blood-brain barrier and may be used for meningeal leukaemia and brain tumours.
Nausea, vomiting, decreased platelets, reduced WBCs, secondary leukaemia, pulmonary fibrosis, renal failure.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
BCNUBis-chlorethylnitrosourea, carmustine A chemotherapeutic related to lomustine–CCNU and semustine, which partially overlaps the activity/toxicity of alkylating agents Indications Hodgkin's disease, possibly NHL, melanoma, myeloma, brain tumors, GI carcinomas; BCNU crosses the blood-brain barrier and may be used for meningeal leukemia and brain tumors Side effects N&V, ↓ platelets, ↓ WBCs, 2º leukemia, pulmonary fibrosis, renal failure
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.