BCL7B

BCL7B

A gene on chromosome 7q11.23 that encodes a ubiquitous phosphoprotein which may play a role in the development or progression of lung cancer.

Molecular pathology
BCL7B is located in the Williams-Beuren syndrome (WBS)-critical region; haploinsufficiency of BCL7B may cause some of the cardiovascular and musculo-skeletal defects seen in WBS.
References in periodicals archive ?
To study disease mechanisms, we chose a gene bcl-7 (mammalian BCL (B cell lymphoma) gene homolog), which is homologous to human BCL7 gene family members (BCL7A, BCL7B and BCL7C).
(2015) The tumor suppressor BCL7B functions in the Wnt signaling pathway.
We selected six genes in the DLBCL data, which are SPIB, IRF8, NFKB2, LMO2, FCGRT, and BCL7B. The GO annotations of these six genes are shown in Table 1.