BCG vaccine


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BCG vaccine

 
bacille calmette-guérin vaccine, a tuberculosis vaccine containing living, avirulent, bovine-strain tubercle bacilli (Mycobacterium bovis). It may be administered percutaneously by a special technique using a multiple-puncture disk, intracutaneously, or intradermally, and it cannot be given when the patient is reactive to tuberculin, when acute infectious disease is present, or when there is extensive skin disorder. It offers some protection against tuberculosis but cannot be relied on for total control of the disease. In a high percentage of cases the vaccine causes local ulcers at the site of administration. Public health officials in the United States recommend the use of BCG vaccine only for those persons living in communities having a high rate of tuberculosis cases. After vaccination with BCG, the patient will have a positive response to tuberculin tests. See also BCG solution.

BCG vac·cine

a suspension of an attenuated strain (bacillus Calmette-Guérin) of Mycobacterium tuberculosis, bovine type, which is inoculated into the skin for tuberculosis prophylaxis.

BCG vaccine

(bē′sē-jē′)
n.
A preparation consisting of attenuated human tubercle bacilli that is used for immunization against tuberculosis.

BCG vaccine

A vaccine containing Bacille Calmette-Guérin, an attenuated strain of the bovine tubercle bacillus. The vaccine is used to confer a measure of immunity on people who, on Mantoux or Heaf testing are shown not to have had a primary infection with tuberculosis. It is equally effective in giving protection against leprosy. BCG vaccine is available in a freeze-dried form. The drug is on the WHO official list. (Leon Charles Albert Calmette, 1863–1933, French surgeon, and Camille Guerin, 1872–1961, French veterinary surgeon).

Calmette,

Leon Charles Albert, French bacteriologist, 1863-1933.
Bacille bilié de Calmette-Guérin - an attenuated strain of Mycobacterium bovis used for immunization against tuberculosis and in cancer chemotherapy. Synonym(s): Bacille Calmette-Guérin; Calmette-Guérin bacillus
Bacille Calmette-Guérin - Synonym(s): Bacille bilié de Calmette-Guérin
bacillus Calmette-Guérin vaccine - a vaccine for tuberculosis prophylaxis. Synonym(s): BCG vaccine
Calmette test - conjunctival reaction to tuberculin.
Calmette-Guérin bacillus - Synonym(s): Bacille bilié de Calmette-Guérin
Calmette-Guérin vaccine - Synonym(s): bacillus Calmette-Guérin vaccine
References in periodicals archive ?
To comprehend Global BCG Vaccine market dynamics in the world mainly, the worldwide BCG Vaccine market is analyzed across major global regions.
In the present work, we are reporting that under specific settings IFN-alpha boosting of BCG vaccine can drive the development of specific antimycobacterial cellular immune responses and restrict M.
Here also BCG vaccine at the above mentioned dose rate was given two times.
A two-day-old male neonate was inadvertently administered an excessive dose of BCG vaccine using a normal (5 ml) syringe instead of an auto-disposable syringe (0.05 ml) at a rural health center with a limited number of deliveries per year.
BCG vaccine is given intradermally over the deltoid muscle on the left arm to infants within 5 days after birth at the maternity hospital.
A 35-year-old male, diagnosed to have sub-polar LL [pre-treatment bacillary index (BI) of 6 + and morphological index (MI) 5% from the ear lobe and arms] was treated with WHO MB-MDT for 1 year and four doses of BCG vaccine were given intradermally as immunotherapy at 3 monthly intervals during the same year.
Another Saudi mother from Jeddah voiced her concern over the absence of the vaccine saying: "I have been visiting and calling several government clinics that offer the vaccines free of charge to Saudi nationals only to find out that they are still waiting to receive the BCG vaccine from the Ministry of Health without giving us any reason for the delay."
DISCUSSION: BCG vaccine was introduced to the world in 1921.
"Importantly, BCG vaccine was never found in common cuts of deer meat, regardless of whether it was given orally or by subcutaneous vaccination, in any of our safety experiments," Palmer says.
This TB vaccine under research was designed to boost immune responses already primed by the BCG vaccine, the currently licensed and widely used TB vaccine.