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BCAPSBeta-blocker Cholesterol-lowering Asymptomatic Plaque Study. A trial comparing the effects of fluvastatin to metoprolol CR/XL on the rate of carotid intima-media thickening in patients with carotid atherosclerosis.
Metoprolol CR/XL trumps fluvastatin in reducing carotid intima-media thickening, especially at the carotid bifurcation.
Randomised, double-blind, placebo-controlled, parallel-group, factorial; 793 patients with asymptomatic right carotid plaques.