RNF2

(redirected from BAP-1)

RNF2

A gene on chromosome 1q25.3 that encodes an E3 ubiquitin-protein ligase that has a RING finger motif. RNF2 is a polycomb group protein that forms multimeric complexes, which play a key role in repressing transcription of various genes in anterior-posterior axis specification, early embryonic development and cell proliferation.
References in periodicals archive ?
Samples were analyzed by mass spectrometry for the presence of the internal standard 6-OH chrysene, BaP, and the following metabolites of BaP: BaP-3-OH; BaP-9-OH; BaP-1,6-dione; BaP-3,6-dione; BaP-6,12-dione; BaP-7,8-dihydrodiol; BaP-9, 10-dihydrodiol; and BaP-7,8,9,10-tetrahydrotetrol.
Recovery of all of the other metabolites (BaP-7,8,9,10-tetrahydrotetrol; BaP-7,8-dihydrodiol; BaP-9,10-dihydrodiol; BaP-1,6-dione; BaP-3,6-dione; BaP-6,12-dione; BaP-90H; and BaP-3-OH) remained below detection limits; therefore, no conclusions could be made concerning their production in the larvae.