beta-galactosidase(redirected from B-galactosidase)
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An enzyme that hydrolyzes the β-galactoside linkage in lactose-producing glucose and galactose; also hydrolyzes the chromogenic substrate IPTG (isopropylthiogalactoside) and thus is used as an indicator of fused genes and gene expression.
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GLB1A gene on chromosome 3p21.33 that encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyses the terminal beta-galactose from gangliosides and other glycoconjugates.
GLB1 mutations cause GM1-gangliosidosis and mucopolysaccharidosis IV (Morquio B syndrome).
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