B-cell

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B-cell

a LYMPHOCYTE formed in the bone marrow of mammals that, after stimulation with a particular ANTIGEN, divides to produce daughter cells that manufacture large amounts of ANTIBODIES which are passed into the bloodstream.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

B-cell (B-lymphocyte)

Type of white blood cell that produces antibodies.
Mentioned in: Multiple Myeloma
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
High concentrations of glucose induce the production of GAD65 in b-cells which is associated with an increase in GAD65 gene expression.
It is noteworthy that although the progression rate was low, MBL might make patients more susceptible to infection because of the depletion of normal B-cells due to the overexpansion of monoclonal elements.
This cytokine then stimulates B-cells in the lymph nodes to produce a molecule called a lymphotoxin.
Still, the study includes the largest reported series of adult B-cell ALL patients treated with genetically engineered T-cells called CD19 CAR-T cells.
Following an infection, numbers of T- and B-cells contract, leaving behind a much-reduced population of central memory cells that persist in lymphatic organs ready to respond rapidly to another attack.
Parotid excisional biopsy multiparameter flow cytometry revealed a 42% of lambda-restricted B-cells, with low forward scatter and SSC, [CD20.sup.+], [CD10.sup.+], [BCL2.sup.+] (Fig.
We used as positive controls anti-HLA Class I (# hla-c1, Invivogen, San Diego, USA) and anti-HLA Class II (# hla-c2, Invivogen, San Diego, USA) controls to highlight the quality of the cell suspension, respectively, enriched for T- or B-cells in the corresponding well.
B-cells were [CD45.sup.+][CD3.sup.-][CD203A.sup.-][CD21.sup.+] whereas NK-cells were [CD45.sup.+][CD3.sup.-][CD203A.sup.-][NKp46.sup.+].
B-cell differentiation factors transform B-cells into plasma cells which start producing anti-bodies (McCullough and Summerfield 2005; Miriam and Kathryn 2005).
Our data showed that TOXO patients presented increased counts of activated [CD4.sup.+]HLA-DR+ T-cells along with [CD4.sup.+][CD8.sup.+] T-cells, CD19+ B-cells, and [CD19.sup.+][CD5.sup.+] B1-cells compared to NI patients (Figures 3(a) and 3(b)).
Naive B-cells undergo maturation by somatic hypermutation in immunoglobulin variable region of the B-cell receptor (BCR) genes following contact with a specific protein accessible on dendritic cells.