POU2AF1(redirected from B-cell-specific coactivator OBF-1)
POU2AF1A gene on chromosome 11q23.1 that encodes a transcription coactivator that recognises the POU domains of OCT1 and OCT2, boosting OCT1 mediated promoter activity and, to a lesser extent, that of OCT2. POU2AF1 is essential for B-cell response to antigens and required for germinal centre formation.
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