IL6

(redirected from B-cell differentiation factor)

IL6

A gene on chromosome 7p21 that encodes interleukin-6, a cytokine which plays a role in the acute-phase response of inflammation and in B-cell maturation. It is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through Il-6 receptor alpha.

Molecular pathology
IL6 dysfunction is linked to increased susceptibility to diabetes and juvenile rheumatoid arthritis.
References in periodicals archive ?
T-cells produce B-cell differentiation factors when B-cells count increases.
B-cell differentiation factors transform B-cells into plasma cells which start producing anti-bodies (McCullough and Summerfield 2005; Miriam and Kathryn 2005).

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