It has also been found that, in the presence of cations, condensation of plasmid B-DNA
is enhanced by the insertion of d(CG)n sequence .
In Figure 3, the CD spectrum of free DNA has a positive peak at 279 nm and a negative peak at 247 nm which corresponds to B-DNA
From the D-(GCAAACGTTTGC)2 B-DNA
dodecamer resolved in PDB file 1HQ7 (Fig.
It is known that in a Bto-A transition, the B-DNA
marker band at 835 (phosphodiester mode) shifts toward a lower frequency at -800 [cm.sup.-1] and a new band appear at -870-860[cm.sup.1].
The circular dichroism spectra of severely affected AD DNA showed a typical left-handed Z-DNA conformation; whereas normal, young, and aged brain DNA have the usual B-DNA
Gagna's discovery will help scientists understand how transitions in DNA structure regulate gene expression (B-DNA
to Z-DNA), and how DNA-protein, and DNA-drug interactions regulate genes.
Helix geometry and hydration in A-DNA, B-DNA
, and Z-DNA.
Use of axial Pattersons in assessment of compatibility of alternative B-DNA
structure with fibre X-ray data.
Z-DNA twists in the opposite direction from the typical, right-handed double helix, known as B-DNA
. The left-handed conformation requires quite a bit of extra energy to keep from reverting to a right-handed twist, notes Zhang.
Hydrogen peroxide and tumor necrosis factor-alpha induce NF-kappa B-DNA
binding in primary human T lymphocytes in addition to T cell lines.
. The elastic response of individual double-stranded and single-stranded DNA molecules.
The right-handed form nestles into grooves of the right-handed helix of normal double-stranded DNA (called B-DNA
), but the left-handed from just doesn't fit.