cyanocobalamin

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Related to B-12: B12

cyanocobalamin

 [si″ah-no-ko-bal´ah-min]
vitamin B12, a substance having hematopoietic activity found in liver, fish meal, eggs, and other natural sources, or produced from cultures of Streptomyces griseus; it combines with intrinsic factor for absorption and is needed for erythrocyte maturation. Absence of intrinsic factor leads to malabsorption of cyanocobalamin and results in pernicious anemia. Called also extrinsic factor. See also vitamin.
cyanocobalamin Co-57 a radiopharmaceutical used in the schilling test for the diagnosis of pernicious anemia.

cy·a·no·co·bal·a·min

(sī'an-ō-kō-bal'ă-min),
A complex of cyanide and cobalamin, as in vitamin B12, in which a cyanide group has filled the sixth coordinate position of the cobalt atom.

cyanocobalamin

(sī′ə-nō′kō-băl′ə-mĭn, sī-ăn′ō-)

vitamin B12

A water-soluble vitamin of animal origin required for DNA synthesis. It is a glycoprotein produced and secreted by the gastric parietal cells, and is absorbed from the GI tract bound to intrinsic factor; the body stores up to one years’ worth of vitamin B12 in the liver, kidneys and heart. Rapid cell turnover (e.g., growth spurts in children, malignancy) require increased amounts of vitamin B12. Vegans, who ingest no protein of animal origin, are at risk for vitamin B12 deficiency.

Increased by
Chronic myeloid leukaemia, chronic obstructive pulmonary disease, congestive heart failure, liver disease, obesity, polycythemia vera, renal failure.
 
Decreased by
Atrophic gastritis, drugs (antibiotics, anticonvulsants, antimalarials, antituberculous agents, chemotherapy, contraceptives, diuretics, oral hypoglycemics, sedatives), inflammatory bowel disease (e.g., Crohn’s disease, ulcerative colitis), intrinsic factor deficiency (causing megaloblastic anaemia), malabsorption, malnutrition, parasites (e.g., Diphyllobotrium latum), veganism.

cyanocobalamin

Vitamin B12 A water soluble B vitamin, central to proper CNS function, and carbohydrate, protein and fat metabolism. See Vitamin B12.

cy·a·no·co·bal·a·min

(sī'ă-nō-kō-bal'ă-min)
A complex of cyanide and cobalamin, as in vitamin B12.

cyanocobalamin

Vitamin B12. This vitamin is necessary for the normal metabolism of carbohydrates, fats and proteins, for blood cell formation and for nerve function. It is used in the treatment of PERNICIOUS ANAEMIA and SPRUE. Brand names are Cytacon and Cytamen.

cyanocobalamin

see COBALAMIN.

cy·a·no·co·bal·a·min

(sī'ă-nō-kō-bal'ă-min)
A complex of cyanide and cobalamin, as in vitamin B12.

Patient discussion about cyanocobalamin

Q. Can a food rich in vitamin B12 will help for his depression or vitamin B12 pills are always required? Hi all…..having one question related to my friends depression and its relation to vitamin B12, as a medicine given to him by his Doctor. Can a food rich in vitamin B12 will help for his depression or vitamin B12 pills are always required?

A. Yes low level of vitamin B12 is associated with depression. You can complete its deficiency by having good diet which will cover the B12 requirements. What happens that depressed people tend to eat less of healthy food and which reduces the B12. So, it again reduces the capacity to fight against the depression.

More discussions about cyanocobalamin
References in periodicals archive ?
Trout is higher in many B vitamins than other freshwater fish, with one serving supplying 30 percent of the DRI of niacin, 38 percent of pantothenic acid, 30 percent of thiamin, 28 percent of riboflavin, 15 percent of B-6 and more than 100 percent of B-12.
Vitamin B-12 (also known as cobalamin because it contains the mineral cobalt) also helps keep our homocysteine levels in check.
It will be fascinating to see how genes, folate and B-12 interact to influence brain development, but until the scientists figure it out, they need to exercise more caution in their publicity campaigns.
The recommended daily allowance for vitamin B-12 in healthy adults is 2.4 micrograms, most of which can be supplied by the diet; however supplementation may be advisable for some people.
The company said that by making it easy to obtain these services in its retail locations with no appointment necessary, it hopes to help seniors and other patients who have B-12 deficiency and also young women and men who want to lower their risk for serious disease caused by HPV.
We're using the vitamin B-12 drug to treat dogs that have cancer.
High levels of homocysteine are associated with dysfunction of the blood vessel linings, whereas treatment with vitamin B-6, vitamin B-12 and folic acid appears to reduce homocysteine levels and may reverse this blood vessel dysfunction.
It is recommended to add B-12 when taking high doses of B-9; they can hide B-12 insufficiency.
Trends in blood folate and vitamin B-12 concentrations in the United States, 1988-2004.
Baseball superstar Roger Clemens denies he cheated by using banned substances and says his accuser, former trainer Brian McNamee, only injected him with the painkiller lidocaine and the vitamin B-12.
Other ingredients of 180 Red include carbonated water, sucrose, guarana and vitamins B-6, B-12 and C.
In addition, 180 Blue contains guarana, red grape and blueberry juices as well as vitamins B-6 and B-12. It is available in 8-oz.