B lymphocyte


Also found in: Dictionary, Thesaurus, Encyclopedia.

B lym·pho·cyte

an immunologically important lymphocyte that is not thymus dependent, is short-lived, and resembles the bursa-derived lymphocyte of birds in that it is responsible for the production of immunoglobulins; that is, it is the precursor of the plasma cell and expresses surface immunoglobulins (SIGS) but does not release them. It does not play a direct role in cell-mediated immunity. B lymphocyte can be characterized immunophenotypically by CD19 surface markers.
See also: T lymphocyte.
Synonym(s): B cell (2)

B lymphocyte

also

B-lymphocyte

(bē′lĭm′fə-sīt′)
n.
See B cell.

B lymphocyte

See B cell.

B cell

One of the two major classes of lymphocytes, which comprises 30% of circulating lymphocytes and is concentrated in the follicular zones of lymphoid tissue (in contrast T cells, which are located in the deep cortex). B cells are responsible for antibody production, a transformation evoked by interaction with the appropriate CD4 T-helper cells. Igs are responsible for specific defence against viruses and bacteria, immune surveillance (cytolysis of potentially malignant “self” cells, mediation of antibody-dependent cell cytotoxicity), allergic reactions, formation of antigen-antibody complexes and production of cytokines; surface and cytoplasmic antigens indicate the degree of B-cell maturation and function. Cytoplasmic IgM is present in pre-B cells and surface Ig in mature B lymphoctytes and plasma cells; complement receptors are seen in mature cells. B cell markers include CD9, CD10, CD19, CD20, CD24, Fc receptor, B1, BA-1 and B4 Ia.

B lym·pho·cyte

(lim'fŏ-sīt)
A lymphocyte that resembles the bursa-derived lymphocyte of birds in that it is responsible for the production of immunoglobulins, i.e., it is the precursor of the plasma cell and expresses immunoglobulins on its surface but does not release them. It does not play a direct role in cell-mediated immunity.
See also: T lymphocyte

B lymphocyte

A type of lymphocyte that circulates in the blood and lymph and produces antibodies when it encounters specific antigens. B lymphocytes are also called B cells.
Mentioned in: Lymphocytopenia

B lym·pho·cyte

(lim'fŏ-sīt)
Immunologically important lymphocyte that is not thymus dependent, is short lived, and resembles the bursa-derived lymphocyte of birds in that it is responsible for the production of immunoglobulins.

B lymphocyte

see B lymphocyte.
References in periodicals archive ?
Julius says that his earlier experiments looked at the effects of human-and sheep-milk proteins on cultured mouse B lymphocytes, but that current work using human-milk proteins and human cells is showing similar results.
Transforming growth factor-b6 specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes.
While the thymus gland has long been considered the executive director of T-lymphocyte production, B lymphocytes are thought to come from the bone marrow in humans.