DNAH.af.5(redirected from Axonemal beta dynein heavy chain 5)
DNAH.af.5A gene on chromosome 5p15.2 that encodes a dynein protein, which is part of a microtubule-associated motor-protein complex consisting of light, intermediate and heavy chains. DNAH5 is a heavy chain force-generating protein with ATPase activity; release of ADP produces the force-producing power stroke.
DNAH5 mutations cause primary ciliary dyskinesia type 3 and Kartagener syndrome.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.