AXL


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AXL

A gene on chromosome 19q13.1 that encodes a receptor tyrosine kinase with a unique extracellular region that juxtaposes IgL and FNIII repeats, transducing signals from the extracellular matrix into the cytoplasm by binding growth factors (e.g., vitamin K-dependent protein growth-arrest-specific gene 6 (GAS6)). AXL is involved in stimulating cell proliferation and mediating cell aggregation by homophilic binding.
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Despite the impressive five octave range, this still doesn't put Axl Rose anywhere near the world record, however.
Pre-clinical studies with the inhibitor bemcentinib demonstrated in vitro and in mouse models that leukaemia proliferation was blocked by interference with AXL signalling.
Although it has a broader product offering, AXL remains heavily exposed to the North American light truck market, particularly with GM, making it sensitive to any changes in that company's light-truck production.
"Someone decided to submit the photo of Mickey Rourke and Axl Rose for the 'birthdays and anniversaries' announcements for our local news station,"the Reddit user revealed- with a string of fans replying to comment.
Brownstone." Then there's Axl Rose who was a right sight to see and hear live as he aced the vocals for the first two classic tracks from their breakout debut album "Appetite For Destruction." Axl might have acquired a bit of body heft, but he can still wail, no problem.
In HER2-positive breast cancers, cells with high levels of AXL are more likely to detach from tumours to form metastases.
The increased expression of AXL has been reported in several cancer types, such as lung, breast, and colorectal as well as head and neck cancer [11].
Other than this, Axl (Charlie McDermott), will also be (http://tvline.com/2017/10/03/the-middle-final-season-9-premiere-recap-axl-returns-from-europe/) returning from Europe , and his entire family will be surprised at how different he is.
Among these DEGs, we found an alternative splicing forms in cordon-bleu WH2 repeat protein-like 1 (COBLL1), cytoplasmic dynein 1 light intermediate chain 2 (DYNC1LI2), pleckstrin homology domain containing, family member 1 (PLEKHG1), and AXL receptor tyrosine kinase (AXL) genes [2].
A SHOWBIZ party with Guns N' Roses rocker Axl Rose was shut down by council officials at 6am after complaints about the noise, it has been claimed.
The measurement of ocular features, especially axial length (AXL) and corneal curvature (K value), is essential for IOL power calculation [4].
AXL is a member of the receptor tyrosine kinase TAM subfamily comprising TYRO-3, AXL, and MER.