amastigote

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Leish·man-Don·o·van bod·y

(līsh'măn don'ŏ-văn),

the intracytoplasmic, nonflagellated leishmanial form of certain intracellular parasites, such as species of Leishmania or the intracellular form of Trypanosoma cruzi; originally used for Leishmania donovani parasites in infected spleen or liver cells in kala azar.

Synonym(s): amastigote, L-D body

Farlex Partner Medical Dictionary © Farlex 2012

Leish·man-Don·o·van bod·y

(lēsh'măn don'ŏ-văn bod'ē)

The intracytoplasmic, nonflagellated leishmanial form of certain intracellular parasites, such as species of Leishmania or the intracellular form of Trypanosoma cruzi.
Synonym(s): amastigote.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Leishman,

Sir William Boog, Scottish surgeon, 1865-1926.

Leishmania - a genus of digenetic, asexual, protozoan flagellates.

Leishman chrome cells - basophilic granular leukocytes (basophils) observed in the circulating blood of some persons with blackwater fever.

Leishman stain - a polychromed eosin-methylene blue stain used in the examination of blood films.

Leishman-Donovan body - the intracytoplasmic, nonflagellated leishmanial form of certain intracellular parasites. Synonym(s): amastigote; L-D body

leishmaniasis - tropical disease that is spread by sandflies.

Medical Eponyms © Farlex 2012

References in periodicals archive ?

The addition of extrinsic recombinant IGF-I to cultures at a physiological concentration induces the proliferation of various species of Leishmania promastigotes and axenic amastigotes [13-15], promotes an increase in macrophage arginase-1 (ARG1) expression as well as in Leishmania arginase (Larg), in vitro [16, 17], and induces a significant increase in the lesion size and the number of viable parasites at the lesion site in experimental models [18].

Insulin-Like Growth Factor-I as an Effector Element of the Cytokine IL-4 in the Development of a Leishmania major Infection

In this context, EtOH-Ext, Hex-F, and Lupeol demonstrated in vitro efficacy against both promastigotes and axenic amastigotes of L.

Platonia insignis Mart., a Brazilian Amazonian Plant: The Stem Barks Extract and Its Main Constituent Lupeol Exert Antileishmanial Effects Involving Macrophages Activation

Souza et al., "Nitric oxide synthase (NOS) characterization in Leishmania amazonensis axenic amastigotes," Archives of Medical Research, vol.

Calcium Ionophore, Calcimycin, Kills Leishmania Promastigotes by Activating Parasite Nitric Oxide Synthase

Antigenic differences between axenic amastigotes & promastigotes of Leishmania donovani.

Vectorborne transmission of Leishmania infantum from hounds, United States

The axenic amastigotes were obtained by promastigote culture in the Schneider medium with a pH of 7.2.

Antileishmanial activity and trypanothione reductase effects of terpenes from the Amazonian species Croton cajucara Benth (Euphorbiaceae)

Robert-Gero, "Pentamidine uptake in Leishmaniadonovani and Leishmaniaamazonensis promastigotes and axenic amastigotes," Biochemical Journal, vol.

Comparative analysis of the omics thechnologies used to study antimonial, amphotericin B, and pentamidine resistance in Leishmania

A simple and reproducible method to obtain large numbers of axenic amastigotes of different Leishmania species.

Interaccion de Leishmania (L.) chagasi con la linea celular Lulo en diferentes condiciones ambientales

We found that Cas9 is also expressed in axenic amastigotes (Figure 1(c)).

Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit

We have previously shown that adding physiological concentrations of extrinsic IGF-I into cultures induces proliferation of different species of Leishmania promastigotes and axenic amastigotes, which is an effect that is not observed with IGF-II despite its high similarity to IGF-I [19, 20].

Insulin-like growth factor-I induces arginase activity in Leishmania amazonensis amastigote-infected macrophages through a cytokine-independent mechanism

amazonensis axenic amastigotes using Rhodamine 123 (Rh 123) reagent following the protocol of manufacturer.

Effects of (-) mammea A/BB isolated from Calophyllum brasiliense leaves and derivatives on mitochondrial membrane of Leishmania amazonensis

Fortunately, in leishmaniasis a close correlation exists between the in vitro and in vivo results (2), because the test parasite is the disease-producing organism in human (amastigote) and these are maintained in vitro as axenic amastigotes and in macrophage culture presenting a semi- in vivo condition.

Visceral leishmaniasis: experimental models for drug discovery

Generation of Leishmania donovani axenic amastigotes: their growth and biological characteristics.