zygosity

(redirected from Autozygosity)
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Related to Autozygosity: heterozygous

zygosity

 [zi-gos´ĭ-te]
the condition relating to conjugation, or to the zygote, such as (a) the state of a cell or individual in regard to the alleles determining a specific character, whether identical (homozygosity) or different (heterozygosity); or (b) in the case of twins, whether developing from one zygote (monozygotic twins) or two zygotes (dizygotic twins).

zy·gos·i·ty

(zī-gos'i-tē),
The nature of the zygotes from which individuals are derived; for example, whether by separation of the division of one zygote (monozygotic), in which case they will be genetically identical, or from two separate zygotes (dizygotic).

zygosity

(zī-gŏs′ĭ-tē)
n.
The genetic condition of a zygote, especially with respect to its being a homozygote or a heterozygote.

zy·gos·i·ty

(zī-gos'i-tē)
The nature of the zygotes from which twins are derived; e.g., whether by division of one zygote (monozygotic), in which case they will be genetically identical, or from two zygotes, in which case they will be genetically different.

zy·gos·i·ty

(zī-gos'i-tē)
Nature of the zygotes from which individuals are derived; e.g., whether by separation of the division of one zygote, in which case they will be genetically identical, or from two separate zygotes.
References in periodicals archive ?
WES and autozygosity mapping studies revealed three independent families in which IHH was associated with inactivating SRA1 variants (64).
In an effort to identify novel genes playing a role in driving the HPG axis, based on autozygosity mapping (77), we identified homozygous non-synonymous mutations in the coding sequences of TAC3 or TACR3 in nine patients from four families with an nIHH phenotype (78).
This "autozygosity" (identical copies of DNA inherited from both parents) might serve not only as a way to predict susceptibility to cancer in some people, but may lead researchers to novel cancer-causing genes.
In a paper "The Signatures of Autozygosity Among Patients with Colorectal Cancer," to be published in print on April 15, in the journal Cancer Research, Dr.
The authors interrogate the exact genetic underpinnings of this particular phenotype by whole exome sequencing coupled with autozygosity mapping.
In an effort to gain a greater understanding into the elusive pubertal process, our laboratory has undertaken a search for genes playing important roles in the generation of gonadotropin secretion in a cohort of familial IHH cases via autozygosity mapping.