Also found in: Acronyms.
autosomal dominantadjective Referring to a trait or disorder that may be passed from one generation to the next when only one allele is required to pass a genetic defect to the progeny.
Achondroplasia, Huntington’s disease, Marfan syndrome, neurofibromatosis, osteogenesis imperfecta.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
autosomal dominantGenetics Referring to a mode of inheritance, in which the presence of only one copy of a gene of interest on one of the 22 autosomal–non-sex chromosomes, will result in the phenotypic expression of that gene; the likelihood of expressing an autosomal gene in progeny is 1:2; ♂ and ♀ are affected equally. Cf Autosomal recessive, X-linked recessive.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
Pert. to or characteristic of an autosomal dominant gene.See: autosomal dominant gene
Medical Dictionary, © 2009 Farlex and Partners
Autosomal dominant or autosomal recessive
Refers to the inheritance pattern of a gene on a chromosome other than X or Y. Genes are inherited in pairs—one gene from each parent. However, the inheritance may not be equal, and one gene may overshadow the other in determining the final form of the encoded characteristic. The gene that overshadows the other is called the dominant gene; the overshadowed gene is the recessive one.
Mentioned in: Cerebral Amyloid Angiopathy, Hereditary Hemorrhagic Telangiectasia, Ichthyosis, Muscular Dystrophy, Peripheral Neuropathy, Porphyrias, Prolonged QT Syndrome, Tourette Syndrome, Von Willebrand Disease, Waldenström's Macroglobulinemia
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.