autonomic neuropathy


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autonomic neuropathy

A symptom complex caused by damage to autonomic nerves.
 
Aetiology
Diabetes, alcohol use, traumatic nerve injury, anticholinergics.

Clinical findings
Abdominal bloating, heat intolerance, nausea, vomiting, impotence, diarrhoea, constipation, orthostatic vertigo, dysuria, urinary incontinence.

autonomic neuropathy

Neurology A symptom complex caused by damage to autonomic nerves Etiology DM, alcohol use, traumatic nerve injury, anticholinergics Clinical Abdominal bloating, heat intolerance, N&V, impotence, diarrhea, constipation, orthostatic vertigo, dysuria, urinary incontinence
References in periodicals archive ?
The progressive accumulation of TTR amyloid deposits in these organs often leads to intractable peripheral sensorimotor neuropathy, autonomic neuropathy, and/or cardiomyopathy, as well as other disease manifestations.
More neuropathies that can be seen in both type 1 DM and type 2 DM are autonomic neuropathy, polyradiculoplexus neuropathy, mono-neuropathies, cranial neuropathies, and treatment induced neuropathies13.
Diabetic autonomic neuropathy (DAN) is a serious and common complication of diabetes that is most often ignored by most of the clinicians.
It may be noted that some forms of autonomic neuropathy and auditory nerve neuropathy might coexist in metabolic diseases such as diabetes mellitus without any causal association.
* Measures for two risk factors for heart disease (hypertension and arterial stiffness) were greater for youth with type 2, but close to equal for a third risk factor (cardiovascular autonomic neuropathy).
The complications give rise to morbidity and compromise the quality of life for diabetic subjects.3 Long-term complications of diabetes include retinopathy with potential loss of vision; nephropathy leading to renal failure; peripheral neuropathy with risk of foot ulcers, amputations, and Charcot joints; and autonomic neuropathy causing gastrointestinal, genitourinary, and cardiovascular symptoms and sexual dysfunction.4
Mutations in the TTR gene cause abnormal amyloid proteins to accumulate and damage body organs and tissue, such as the peripheral nerves and heart, resulting in intractable peripheral sensory neuropathy, autonomic neuropathy, and/or cardiomyopathy, as well as other disease manifestations.
- Anaemia is common in diabetic autonomic neuropathy
The authors hypothesized that the "global score" (hemoglobin, mean corpuscular volume, gastrin, vitamin [B.sub.12], and chromogranin A) and "simple score" (hemoglobin, mean corpuscular volume, and gastrin) systems are helpful in differentiating autoimmune gastritis (AIG) patients with autonomic neuropathy from patients with normal autonomic nervous system function.
Blake et al., "Clinical, pathological and genetic characterization of hereditary sensory and autonomic neuropathy type I (HSAN I)," Brain, vol.
Several previous studies suggested an association between OSA and diabetic autonomic neuropathy [16, 17].
Autonomic neuropathy is an underestimated complication of DM and may remain asymptomatic in early stages, especially in young patients with type 1 DM (T1DM) [3].

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