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malfunction of the autonomic nervous system.
familial dysautonomia Riley-Day syndrome.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


Abnormal functioning of the autonomic nervous system.
[dys- + G. autonomia, self-government]
Farlex Partner Medical Dictionary © Farlex 2012


A gene on chromosome 9q31 that encodes a putative scaffold protein which may assemble active IKK-MAP3K14 complexes and act as subunit of the RNA polymerase II elongator complex, a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme involved in transcriptional elongation. The elongator complex may play a role in chromatin remodelling; it may be involved in acetylation of histone H3 and possibly also H4.

Molecular pathology
Defects in IKBKAP cause familial dysautonomia, also known as hereditary sensory and autonomic neuropathy type 3, or Riley-Day syndrome.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Neurology Any condition characterized by sympathetic or parasympathetic derangements; autonomic hypofunction or failure is most often caused by drugs and disease-associated polyneuropathies–eg, DM and amyloidosis, but may be idiopathic Classifications Primary dysautonomia system, sanctioned by the American Academy of Neurology; Goldstein classification. See Familial dysautonomia aka Riley-Day syndrome.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


Abnormal functioning of the autonomic nervous system.
[dys- + G. autonomia, self-government]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


Abnormal functioning of autonomic nervous system.
[dys- + G. autonomia, self-government]
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about dysautonomia

Q. What is dysautonomia? My friend has dysautonomia. What does it mean? What are the symptoms? Is it curable?

A. Dysautonomia is any disease or malfunction of the autonomic nervous system. The symptoms of dysautonomia conditions are usually “invisible” to the untrained eye. The child can appear to be as healthy as other children. The manifestations are occurring internally, and although the symptoms are often are not visible on the outside. Symptoms can be unpredictable, may come and go, appear in any combination, and may vary in severity).There is no cure for dysautonomia. There are medications to assist in stabilization, but are often needed on a long-term basis.

More discussions about dysautonomia
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References in periodicals archive ?
In contrast, strength-trained offspring of hypertensives did not demonstrate autonomic dysfunction in both LF and HF bands (A-OH group, LF: 70.2 [+ or -]0.3% and HF: 29.7 [+ or -] 0.3%).
There may be findings of autonomic dysfunction including thermal dysregulation (hypothermia/hyperthermia), cold, pale hands and feet (Raynaud's phenomenon), excessive sweating, decreased pain sensitivity, impaired pupillary response to light, bradycardia, hypotension and gastrointestinal dysmotility (2,6,7).
This study consists of 75 newly detected type 2 diabetic patients without any symptoms of autonomic dysfunctions. One of the serious complications of diabetes mellitus is Autonomic dysfunction; this can affect daily activities and sometimes have lethal outcomes.
(11,12) Kim and Lee showed an association between residual dizziness in BPPV and sympathoneural autonomic dysfunction. (13) Pezzoli et al also hypothesized autonomic dysfunction to have a role in orthostatic dizziness after recovery of BPPV attacks.
(13) found that decreased serum Ca levels causes disturbances in the autonomic nervous system.Although BHS are closely related to autonomic dysfunction and Mg and Ca are suspected to have effects on autonomic functions, there areno studies reporting the relationship between serum Mg and Ca levels in BHS.
Also, the poor sleep quality contributes to the autonomic dysfunction in this population, with increased cases of nocturnal dyspnea (31).
Diane was stricken with this rare degenerative neurological condition causing parkinsonism, ataxia and autonomic dysfunction, Multiple System Atrophy (MSA).
But autonomic dysfunction is mandatory for the diagnosis of MSA according to the revised consensus criteria,1 our both patients has urinary and fecal incontinence.
Cardiac autonomic dysfunction is a frequent complication of SCI, especially after a cervical SCI, and result in increased morbidity and mortality (Garshick et al., 2005; Yang et al., 2013).
The mean "simple" and "global" scores were significantly higher in patients with altered autonomic dysfunction than in those with normal autonomic function (3.55[+ or -]1.88 vs.
Autonomic dysfunction is also observed in metabolic diseases such as diabetes, obesity, and metabolic syndrome.

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