Kalesinskas, "Osteochondral
autologous transplantation versus microfracture for the treatment of articular cartilage defects in the knee joint in athletes," Knee Surgery, Sports Traumatology, Arthroscopy, vol.
(iii) carrying out
autologous transplantation using cloned animals (mouse);
High-dose chemotherapy with
autologous transplantation for persistent/relapsed ovarian cancer: a multivariate analysis of survival for 100 consecutively treated patients.
Presence of graft versus host disease, delayed immune reconstitution and allogeneic transplantation compared to
autologous transplantation are the most important risk factors.
There Are No Significant Differences in Cytokines Expression at Day 7 after MDC
Autologous Transplantation. The dynamics of evaluated genes expression clearly demonstrate that upregulation of proinflammatory cytokines after autologous MDCs transfer is acute and transient.
High-dose therapy with single
autologous transplantation versus chemotherapy for newly diagnosed multiple myeloma: A systematic review and meta-analysis of randomized controlled trials.
Intraspinal transplantation of human [CD34.sup.+] CB cells showed benefit in functional recovery after spinal cord hemisection in rats and suggested that [CD34.sup.+] CB cells might be an excellent choice of cells as a routine starting material of allogenic and
autologous transplantations for the treatment of spinal cord injury66.
The company says in Europe, Mozobil is indicated in combination with granulocytecolony stimulating factor (G-CSF) to enhance mobilization of stem cells to the blood stream for collection and subsequent
autologous transplantation inpatient with lmyphoma and multiple myeloma whose cells mobilize poorly.
But this strategy ignores certain limitations to
autologous transplantation (that is, transplantation of one's own stem cells).
Mildred Pasek, RN, OCN[R], MM, ONS member and DFCI stem cell transplant research nurse, says that the distinguishing features of DFCI's program are its size and age; the availability of autologous, related, and unrelated transplants; the research programs in graft-versus-host prophylaxis and treatment as well as mismatched, double-cord transplants; the vaccine program; and the novel mobilizing agents the program has developed for
autologous transplantation. In 2006, DFCI performed 190 allogeneic, 157 autologous, and 20 cord blood transplants.
Currently, units of UCB from donors with genetic diseases are not indicated for
autologous transplantation. If a donor child harbors an inherited hematologic, immunologic, or genetic disorder, the unit would not be used because there is no expectation that it would be curative.
The most worrisome side effect of
autologous transplantation is treatment-related malignancy.
