atypical antipsychotic

(redirected from Atypical neuroleptic)

atypical antipsychotic

A dibenzepine-type antipsychotic which differs from conventional antipsychotics in its paucity of extrapyramidal effects (tremor, muscle stiffness and restlessness).
 
Adverse effects
Insomnia, anxiety, agitation, sedation, dizziness, rhinitis, orthostatic hypotension, tachycardia, weight gain, menstrual disturbances, seizures; rarely, severe granulocytopaenia or agranulocytosis; should not be used in patients with liver, brain or circulatory defects.
 
Examples
Clozapine (Clozaril), ziprasidone (Geodon), loxapine (Loxitane), olanzapine (Zyprexa), resperidone (Risperdal), quetiapine (Seroquel).

antipsychotic

(ant?i-si?kot'ik) [ anti- + psychotic]
1. Preventing or treating psychosis, e.g., schizophrenia.
2. A medication to treat psychosis.

atypical antipsychotic

Second-generation antipsychotic.

first-generation antipsychotic

A neuroleptic drug. They treat psychotic disorders and other psychiatric diseases. Side effects include extrapyramidal (Parkinsonian) reactions. Synonym: conventional antipsychotic See: neuroleptic (1)

conventional antipsychotic

First-generation antipsychotic.

second-generation antipsychotic

An antipsychotic drug that causes increased appetite, weight gain, and adverse effects on lipids. They differ from first-generation antipsychotics in that they are less likely to cause extrapyramidal side effects or tardive dyskinesia.
Synonym: atypical antipsychotic
References in periodicals archive ?
Atypical neuroleptic malignant syndrome and atypical antipsychotics.
Aftab, "It's all atypical: can clozapine cause atypical neuroleptic malignant syndrome?" Australian and New Zealand Journal of Psychiatry, vol.
Moreover, we compared in two different analyses patients on atypical neuroleptics monotherapy versus patients with a second atypical neuroleptic in add-on and patients with atypical neuroleptics monotherapy versus patients with haloperidol in add-on, with the Mann-Whitney Test.
Atypical neuroleptic malignant syndrome: diagnosis controversies and considerations.
Clozapine was the first atypical neuroleptic to be developed, and has been used since the 1960s.
This quasi-longitudinal descriptive case study evaluated problem behavior for an adolescent boy with developmental disabilities via repeated functional behavioral analysis (FBA) probes during a blinded cross-over from the atypical neuroleptic Risperdal (Risperidone) to Seroquel (Quetiapine).
Atypical neuroleptic malignant syndrome presenting as fever of unknown origin in the elderly.
Atypical neuroleptic agents show benefit in studies for trauma-related psychotic symptoms such as hallucinations.
It rests on published findings from several short-term studies comparing one group of haloperidol-treated patients switched to placebo, with another group of haloperidol-treated patients switched to an atypical neuroleptic. In the first group, one would expect to see a moderate rate of withdrawal-emergent EPS within the first few weeks (as extrapyramidal symptoms regularly emerge or exacerbate at least temporarily when the dose of an antipsychotic is reduced or withdrawn).

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