ABC Superfamily

(redirected from Atp-binding cassette transporters)

ABC Superfamily

A family of oligopeptide permease proteins, which are selective for various substrates including short oligopeptides, transporting them across membranes.
Examples Multi-drug resistance protein, bacterial and eukaryotic transporters
References in periodicals archive ?
Kroemer, "Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5)," Drug Metabolism Reviews, vol.
Tall, "ATP-binding cassette transporters, atherosclerosis, and inflammation," Circulation Research, vol.
Wang et al., "Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice," Circulation Research, vol.
Firstly, cholesterol absorption from daily diet is mainly depended on Niemann-Pick C1-Like 1 (NPC1L1) and ATP-binding cassette transporters G5/G8 (ABCG5/G8) in the intestine.
Tall, "ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins," Proceedings of the National Academy of Sciences of the United States of America, vol.
Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo.
For instance, ATP-binding cassette transporters encoded by genes known as ABCB1 and ABCC1 are involved in eliminating carcinogens from the lungs, protecting them against inhaled toxins.
ATP-binding cassette transporters in macrophages: promising drug targets for treatment of cardiovascular disease.
The roles of ATP-binding cassette transporters, such as ABCC1, ABCC11, and ABCG2, in breast cancer patients have been reported.
Kou et al., "[alpha]-Lipoic acid ameliorates foam cell formation via liver X receptor a-dependent upregulation of ATP-binding cassette transporters A1 and G1," Free Radical Biology and Medicine, vol.
Welch et al., "Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes," Journal of Biological Chemistry, vol.
Klucken et al., "The gene encoding ATP-binding cassette transporter I is mutated in Tangier disease," Nature Genetics, vol.

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