ABC Superfamily

(redirected from Atp-binding cassette transporters)

ABC Superfamily

A family of oligopeptide permease proteins, which are selective for various substrates including short oligopeptides, transporting them across membranes.
Examples Multi-drug resistance protein, bacterial and eukaryotic transporters
Mentioned in ?
References in periodicals archive ?
Firstly, cholesterol absorption from daily diet is mainly depended on Niemann-Pick C1-Like 1 (NPC1L1) and ATP-binding cassette transporters G5/G8 (ABCG5/G8) in the intestine.
Opposing Gatekeepers of Apical Sterol Transport: Niemann-Pick C1-Like 1 (NPC1L1) and ATP-Binding Cassette Transporters G5 and G8 (ABCG5/ABCG8).
Effects of Saponin from Trigonella Foenum-Graecum Seeds on Dyslipidemia
Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo.
Overcoming resistance in breast cancer
For instance, ATP-binding cassette transporters encoded by genes known as ABCB1 and ABCC1 are involved in eliminating carcinogens from the lungs, protecting them against inhaled toxins.
Gene variants behind cigarette smoke metabolism linked to lung cancer risk
ATP-binding cassette transporters in macrophages: promising drug targets for treatment of cardiovascular disease.
Identification of a novel human sterol-sensitive ATP-binding cassette transporter (ABCA7).
Molecular cloning of the human ATP-binding cassette transporter 1(hABC1): evidence for sterol-dependent regulation in macrophages.
Atp-binding cassette transporter ABC2/ABCA2 in the rat brain: a novel mammalian lysosome-associated membrane protein and a specific marker for oligodendrocytes but not for myelin sheaths.
Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues

Medical browser ?
Full browser ?