ABC Superfamily

(redirected from Atp-binding cassette transporters)

ABC Superfamily

A family of oligopeptide permease proteins, which are selective for various substrates including short oligopeptides, transporting them across membranes.
Examples Multi-drug resistance protein, bacterial and eukaryotic transporters
References in periodicals archive ?
Firstly, cholesterol absorption from daily diet is mainly depended on Niemann-Pick C1-Like 1 (NPC1L1) and ATP-binding cassette transporters G5/G8 (ABCG5/G8) in the intestine.
Opposing Gatekeepers of Apical Sterol Transport: Niemann-Pick C1-Like 1 (NPC1L1) and ATP-Binding Cassette Transporters G5 and G8 (ABCG5/ABCG8).
Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo.
For instance, ATP-binding cassette transporters encoded by genes known as ABCB1 and ABCC1 are involved in eliminating carcinogens from the lungs, protecting them against inhaled toxins.
ATP-binding cassette transporters in macrophages: promising drug targets for treatment of cardiovascular disease.
Identification of a novel human sterol-sensitive ATP-binding cassette transporter (ABCA7).
Molecular cloning of the human ATP-binding cassette transporter 1(hABC1): evidence for sterol-dependent regulation in macrophages.
Atp-binding cassette transporter ABC2/ABCA2 in the rat brain: a novel mammalian lysosome-associated membrane protein and a specific marker for oligodendrocytes but not for myelin sheaths.

Full browser ?