atlas

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atlas

 [at´las]
the first cervical vertebra, the uppermost segment of the vertebral column, which supports the skull.
 Atlas. (A), (top) superior aspect; (bottom) transverse aspect. Note the absence of the body and spinous process. (B), position. From Dorland's, 2000.

at·las

(at'las), [TA]
First cervical vertebra, articulating with the occipital bone and rotating around the dens of the axis.
[G. Atlas, in Greek mythology, a Titan who supported the heavens on his shoulders]

atlas

(ăt′ləs)
n. pl. at·lases
Anatomy The top or first cervical vertebra of the neck, which supports the skull.

ATLAS

Cardiology
(1) Assessment of Treatment with Lisinopril and Survival. A trial comparing the effects of high to low doses of Zestril®/lisinopril on morbidity and mortality (M&M) in patients with CHF.
 
Logistics
Randomised, double-blind, parallel-group; 3164 patients.
 
Conclusion
Combined risk of mortality and hospitalisation was 12% lower in the high-dose group.
 
(2) Acolysis during Treatment of Lesions Affecting Saphenous Vein Bypass Grafts. A trial evaluating the use of percutaneous CUT for managing thrombosed coronary SVGs.
 
Primary endpoint
Composite (minimum) lumen diameter <30%, TIMI-3 flow, 30-day freedom from MACE; was achieved in 54% of CUT patients vs 73% of abciximab patients.
 
Logistics
Randomised, controlled, multicentre; 191 patients (92 CUT, 89 abciximab followed by PCI).
 
Conclusion
CUT should not be used during PCI of thrombosed SVGs.

Oncology
Adjuvant Tamoxifen Longer Against Shorter. A trial that asked the optimal duration of adjuvant tamoxifen (a SERM) therapy in women with early breast CA.
 
Logistics
Randomised, international; 13752 enrolled.
 
Sports medicine
Athletes’ Training and Learning to Avoid Anabolic Steroids. A multi-component school-based program for male high school athletes (age 13 to 19), which capitalises on team-centred dynamics and uses positive peer pressure and role modelling to reduce the use of anabolic steroids, alcohol and other drugs.
 
Intervention
A highly scripted 10-session curriculum.
 
Results
New substance use and anabolic steroid use decreased by 50%; drinking and driving decreased by 25%; decreased use of drugs, alcohol and performance-enhancing agents; increased exercise and nutrition.

ATLAS

Cardiology A five-yr, randomized, double-blind trial–Assessment of Treatment with Lisinopril & Survival–which evaluated the effect of high vs low doses of Zestril®/lisinopril on M&M in Pts with CHF; high doses appear to be effective. See Lisinopril Sports medicine A 5-yr controlled trial–Athletes' Training and Learning to Avoid Anabolic Steroids begun in 1993 and funded by the National Institute of Drug Abuse. See Anabolic steroids.

at·las

(at'lăs) [TA]
First cervical vertebra, articulating with the occipital bone and rotating around the dens of the axis.
Synonym(s): vertebra C1.
[G. Atlas, in Greek mythology, a Titan who supported the heavens on his shoulders]

atlas

See ATLAS BONE.

atlas

the first vertebra of TETRAPODS, linking skull and axis.

at·las

(at'lăs) [TA]
First cervical vertebra, articulating with the occipital bone and rotating around the dens of the axis.
[G. Atlas, in Greek mythology, a Titan who supported the heavens on his shoulders]